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Oral antivirals for the prevention and treatment of SARS-CoV-2 infection
Vaccines and antivirals are the classical weapons deployed to contain, prevent, and treat life-threatening
viral illnesses. Specifically, for SARS-CoV-2 infection, vaccines protect against severe COVID-19 disease
manifestations ...
Genomic determinants of hepatitis C virus antiviral therapy outcomes: toward individualized treatment
(2012)
Hepatitis C virus (HCV) is an important global health problem with an estimated prevalence of more than 170 million infected individuals worldwide. Currently, the standard antiviral therapy, based on pegylated interferon ...
Envisioning a hepatitis delta cure with new antivirals
Envisioning a hepatitis delta cure with new antivirals
Antiviral therapy for human rabies
(Int Medical Press Ltd, 2015-01-01)
Human rabies is virtually always fatal despite numerous attempts at aggressive therapy. Most survivors received one or more doses of rabies vaccine prior to the onset of the disease. The Milwaukee Protocol has proved to ...
Plant-derived antivirals against hepatitis c virus infection
(Biomed Central Ltd, 2018-02-13)
Hepatitis C virus (HCV) infection is a worldwide public health burden and it is estimated that 185 million people are or have previously been infected worldwide. There is no effective vaccine for prevention of HCV infection; ...
Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
(2014-01-01)
Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, ...
Detection of hepatitis C virus resistant mutants in the era of direct acting antivirals
(2014-01-07)
Hepatitis C Virus (HCV) infects millions of people and represents an important public health problem in different regions of the world. Drug resistance is a major challenge for HCV-infection related control. Importantly, ...
Ultra-long-acting antivirals as chemical vaccines to prevent viral diseases
For two centuries, vaccines have been successful in the fight against viruses, triggering immune protection. Indeed, the elimination of smallpox, the only infectious disease eradicated to date, was made possible through ...
Hepatitis C hospitalizations in Spain and impact of new curative antiviral therapies
Chronic hepatitis C virus (HCV) infection is major cause of decompensated cirrhosis and liver cancer. The advent of curative new antiviral therapies since year 2015 has dramatically improved the prognosis of HCV patients. ...