Buscar
Mostrando ítems 1-10 de 64
Current advances in antitubercular drug discovery: potent prototypes and new targets
(Bentham Science Publishers, 2015)
Tuberculosis (TB) is an infectious disease caused by bacterium of the Mycobacterium genus, mainly by Mycobacterium tuberculosis (MTB). The World Health Organization aims to substantially reduce the number of cases in the ...
Current advances in antitubercular drug discovery: potent prototypes and new targets
(Bentham Science Publishers, 2015)
Current advances in antitubercular drug discovery: potent prototypes and new targets
(Bentham Science Publishers, 2015)
Shikimate kinase: A potential target for development of novel antitubercular agents
(Bentham Science Publ Ltd, 2007-03-01)
Tuberculosis (TB) remains the leading cause of mortality due to a bacterial pathogen, Mycobacterium tuberculosis. However, no new classes of drugs for TB have been developed in the past 30 years. Therefore there is an ...
Shikimate kinase: A potential target for development of novel antitubercular agents
(Bentham Science Publ Ltd, 2007-03-01)
Tuberculosis (TB) remains the leading cause of mortality due to a bacterial pathogen, Mycobacterium tuberculosis. However, no new classes of drugs for TB have been developed in the past 30 years. Therefore there is an ...
Shikimate kinase: A potential target for development of novel antitubercular agents
(Bentham Science Publ Ltd, 2014)
Rapid Detection of Mycobacterium tuberculosis Strains Resistant to Isoniazid and/or Rifampicin: Standardization of Multiplex Polymerase Chain Reaction Analysis
(American Society of Tropical Medicine and Hygiene, 2016)
Drug susceptibility testing using molecular techniques can enhance the identification of drug-resistant Mycobacterium tuberculosis Two multiplex real-time polymerase chain reaction (qPCR) assays were developed to detect ...
A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance
(BioMed Central, 2017)
BACKGROUND: Tuberculosis (TB) is a major global health problem and drug resistance compromises the efforts to control this disease. Pyrazinamide (PZA) is an important drug used in both first and second line treatment ...
dfrA thyA Double Deletion in para-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains
(American Society for Microbiology, 2016)
Para-Aminosalicylic acid (PAS) is a group 4 antituberculosis agent. It targets folate metabolism as shown in Fig. S1 in the supplemental material, which also summarizes the known mechanisms of resistance to this prodrug. ...