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Interaction of opioids with antidepressant-induced antinociception
(Springer-Verlag, 1995)
The antinociceptive activity of antidepressant drugs is poorly understood. In this study, using the acetic acid writhing test in mice, the antinociception produced by clomipramine (CLO), maprotiline (MAP), imipramine (IMI), ...
Adenosinergic nature of antidepressant-induced antinociception in mice
(1997)
The antinociceptive activity of the antidepressant agents imipramine, maprotiline and amitriptyline and their interactions with morphine and aminophylline were evaluated using the acetic acid writhing test of mouse. All ...
Adrenergic modulation of dexketoprofen antinociception in murine formalin orofacial pain
(2021)
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in pain whose mechanism of action is the inhibition of cyclooxygenase enzymes (COXs), however, there are evidence of other mechanisms of action, such as the ...
Synergy between the antinociceptive effects of morphine and NSAIDs
(2004)
The intraperitoneal administration of morphine, diclofenac, ketoprofen, meloxicam, metamizol, paracetamol and piroxicam induced dose-dependent antinociception in mice tested with the acetic acid writhing test. The ...
Antinociceptive interaction of Tramadol with Gabapentin in experimental mononeuropathic pain
(Blackwell Publishing Ltd, 2016-08)
Neuropathic pain is the result of injury to the nervous system, and different animal models have been established to meet the manifestations of neuropathy. The pharmacotherapy for neuropathic pain includes gabapentin and ...
Carbachol interactions with nonsteroidal anti-inflammatory drugs
(2002)
The inhibition of cyclooxygenase enzymes by nonsteroidal anti-inflammatory drugs (NSAIDs) does not completely explain the antinociceptive efficacy of these agents. It is known that cholinergic agonists are antinociceptive, ...
Assessment of the antinociceptive and ulcerogenic activity of the tapentadol–diclofenac combination in rodents
(Wiley Online Library, 2019)
α-Adrenoceptor and opioid receptor modulation of clonidine-induced antinociception
(John Wiley and Sons Inc., 1996)
1. The antinociceptive action of clonidine (Clon) and the interactions with α1, α2 adrenoceptor and opioid receptor antagonists was evaluated in mice by use of chemical algesiometric test (acetic acid writhing test). 2. ...
Antinociceptive effects of morphine, fentanyl, tramadol and their combination, in morphine-tolerant mice
(Elsevier Inc., 2010)
The development of morphine-tolerance after chronic administration, reduces analgesic efficacy and is a significant clinical problem in some patients; may be managed clinically by increasing the doses of morphine and/or ...
Neostigmine interactions with non steroidal anti-inflammatory drugs
(2002)
1. The common mechanism of action of non-steroidal anti-inflammatory drugs (NSAIDs) is the inhibition of the enzyme cyclo-oxygenase (COX), however, this inhibition is not enough to completely account for the efficacy of ...