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Study of visceral antinociceptive potential of bee Apis mellifera venom
(2014)
Pain is one of the most common reasons for patients to seek medical care. Bee Apis mellifera venom (AMV) has traditionally been used to treat inflammatory diseases and the alleviation of pain. Herein, we aimed to investigate ...
Adrenergic modulation of dexketoprofen antinociception in murine formalin orofacial pain
(2021)
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used in pain whose mechanism of action is the inhibition of cyclooxygenase enzymes (COXs), however, there are evidence of other mechanisms of action, such as the ...
Antinociception, tolerance, and physical dependence comparison between morphine and tramadol
(Elsevier Inc., 1998)
The mechanism of action of tramadol includes the activation of opioid receptors, and the potential ability of the drug to induce tolerance and physical dependence has been evaluated in different animal species and humans. ...
α-Adrenoceptor and opioid receptor modulation of clonidine-induced antinociception
(John Wiley and Sons Inc., 1996)
1. The antinociceptive action of clonidine (Clon) and the interactions with α1, α2 adrenoceptor and opioid receptor antagonists was evaluated in mice by use of chemical algesiometric test (acetic acid writhing test). 2. ...
Antinociceptive effects of Ca2+ channel blockers
(1992)
The antinociceptive action of four Ca2+ channel blockers, nifedipine, nimodipine, verapamil and diltiazem, was evaluated and compared to that of morphine using three algesiometric tests in mice and rats, namely, formalin, ...
Antinociceptive action of hemopressin in experimental hyperalgesia
(Elsevier Science IncNew YorkEUA, 2005)
Adenosine modulates the antinociceptive action of benzodiazepines
(1993)
1. 1. In the present study, adenosine modulation on the antinociceptive action of benzodiazepines (BZD) using the writhing test in mice was evaluated. 2. 2. The i.c.v. BZDs tested (diazepam, midazolam and lorazepam) induced ...
Anti‑infammatory and antinociceptive efects of an ethanol extract from Senna septemtrionalis
(Springer International Publishing, 2022)
Involvement of opioid system, TRPM8, and ASIC receptors in antinociceptive effect of Arrabidaea brachypoda (DC) bureau
(2017-11-02)
Arrabidaea brachypoda (DC) Bureau is a medicinal plant found in Brazil. Known as “ció-una”, it is popularly used as a natural therapeutic agent against pain and inflammation. This study evaluated the chemical composition ...
Dose-related antinociceptive effects of intravenous buprenorphine in cats
(Elsevier B.V., 2009-11-01)
The dose-related antinociceptive effects of intravenous (IV) buprenorphine were evaluated in cats. Thermal (TT) and mechanical threshold (MT) devices were used for nociceptive stimulation. After baseline threshold recordings, ...