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Entinostat (SNDX-275) for the treatment of non-small cell lung cancer
(Taylor and Francis, 2015)
INTRODUCTION: Epigenetic aberrations play an important role in lung carcinogenesis. Chromatin deacetylation is a fundamental mechanism of gene silencing. Histone deacetylase (HDAC) inhibitors are an emerging class of ...
Expression of p53, Ki-67, and CD31 proteins in endometrial polyps of postmenopausal women treated with tamoxifen.
(2010-12-01)
This study was undertaken to investigate the expression of p53, Ki-67, and CD31 proteins in endometrial polyps of postmenopausal women treated with tamoxifen (TAM). Postmenopausal women with endometrial polyps treated with ...
Expression of p53, Ki-67, and CD31 proteins in endometrial polyps of postmenopausal women treated with tamoxifen.
(2010-12-01)
This study was undertaken to investigate the expression of p53, Ki-67, and CD31 proteins in endometrial polyps of postmenopausal women treated with tamoxifen (TAM). Postmenopausal women with endometrial polyps treated with ...
Mathematical analysis and simulations involving chemotherapy and surgery on large human tumours under a suitable cell-kill functional response
(2013-02-01)
Dosage and frequency of treatment schedules are important for successful chemotherapy. However, in this work we argue that cell-kill response and tumoral growth should not be seen as separate and therefore are essential ...
Mathematical analysis and simulations involving chemotherapy and surgery on large human tumours under a suitable cell-kill functional response
(2013-02-01)
Dosage and frequency of treatment schedules are important for successful chemotherapy. However, in this work we argue that cell-kill response and tumoral growth should not be seen as separate and therefore are essential ...
Análise do potencial antibacteriano de novos compostos da classe triazenos
(Universidade Tecnológica Federal do ParanáCampo MouraoBrasilDepartamento Acadêmico de QuímicaLicenciatura em QuímicaUTFPR, 2018-12-07)
Cancerous diseases symbolize one of the biggest causes of death in Brazil and in the world, and research to find more efficient antineoplastic treatments has led to the synthesis of many molecules. Moreover, the large ...
Compostos da classe triazenos: um estudo in silico envolvendo a análise das propriedades farmacocinéticas
(Universidade Tecnológica Federal do ParanáCampo MouraoBrasilDepartamento Acadêmico de QuímicaLicenciatura em QuímicaUTFPR, 2022-06-08)
The triazene compounds have been gaining prominence as promising drugs, as they show antitumor and antimicrobial properties, such as the already marketed Dacarbazine® and Temozolomide®. Every day the incidence of cases of ...