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Buccal and sublingual vaccines: a review on oral mucosal immunization and delivery systems
(MDPI, 2021)
Currently, most vaccines available on the market are for parental use; however, this may
not be the best option on several occasions. Mucosal routes of administration such as intranasal,
sublingual, and buccal generate ...
Poly-lactide-co-glycolide microparticle sizes: A rational factorial design and surface response analysis
(Amer Scientific PublishersStevenson RanchEUA, 2006)
The Importance of Nanocarrier Design and Composition for an Efficient Nanoparticle-Mediated Transdermal Vaccination
(MDPI, 2021)
The World Health Organization estimates that the pandemic caused by the SARS-CoV-2 virus claimed more than 3 million lives in 2020 alone. This situation has highlighted the importance of vaccination programs and the urgency ...
Effect of Delivery Platforms Structure on the Epidermal Antigen Transport for Topical Vaccination
(American Chemical Society, 2018-12)
Transdermal immunization is highly attractive because of the skin's accessibility and unique immunological characteristics. However, it remains a relatively unexplored route of administration because of the great difficulty ...
Recombinant lactic acid bacteria as delivery vectors of heterologous antigens: the future of vaccination?
(CIENCIAS, 2015)
Lactic acid bacteria (LABs) are good candidates for the development of new oral vaccines and are attractive alternatives to attenuated pathogens. This review focuses on the use of wild-type and recombinant lactococci and ...
Estratégias biotecnológicas para a liberação controlada de antígenos e adjuvantes em vacinas através de lipossomas
(2006-10-01)
Liposomes (LP) are colloidal systems with ability to compartmentalize therapeutic molecules in order to improve biological activity, decreases the potential toxicity, and to obtain prolonged effect. In this work it was ...
Estratégias biotecnológicas para a liberação controlada de antígenos e adjuvantes em vacinas através de lipossomas
(2006-10-01)
Liposomes (LP) are colloidal systems with ability to compartmentalize therapeutic molecules in order to improve biological activity, decreases the potential toxicity, and to obtain prolonged effect. In this work it was ...
Development of an Antigen Delivery Platform Using Lactobacillus acidophilus Decorated With Heterologous Proteins: A Sheep in Wolf’s Clothing Story
(Frontiers Media, 2020-10)
S-layers are bacterial structures present on the surface of several Gram-positive and Gram-negative bacteria that play a role in bacterial protection. In Lactobacillus acidophilus (L. acidophilus ATCC 4356), the S-layer ...