In the last decades, the increased number of immunocompromised patients has led to the emergence of many forms of fungal infections. Furthermore, there are a restricted arsenal of antifungals available and an increase in ...

The high rates of morbidity and mortality caused by fungal infections are associated with the current limited antifungal arsenal and the high toxicity of the compounds. Additionally, identifying novel drug targets is ...

Anfifugal stewardship refers to coordinated interventions designed to improve and measere the appropiate use of antifungals by promouting the selection of the optimal antifungal drug regimen,dose,duration of therapy,and ...

A series of aryloxyacetic ester analogues 8–13 was synthesized based on the potential pharmacophores of the antifungal agents a-Asarone (1) and 2–5. Their antifungal activity was tested in vitro for their growth inhibitory ...

A series of aryloxyacetic ester analogues 8–13 was synthesized based on the potential pharmacophores of the antifungal agents a-Asarone (1) and 2–5. Their antifungal activity was tested in vitro for their growth inhibitory ...

A series of aryloxyacetic ester analogues 8–13 was synthesized based on the potential pharmacophores of the antifungal agents a-Asarone (1) and 2–5. Their antifungal activity was tested in vitro for their growth inhibitory ...

Fungal infections are responsible for high mortality rates in immunocompromised and high-risk surgical patients. Therapy failures during the last decades due to increasing multidrug resistance demand innovative strategies ...

The strict nutritional requirements of Malassezia species make it difficult to test the antifungal susceptibility. Treatments of the chronic and recurrent infections associated with Malassezia spp. are usually ineffective. ...