Buscar
Mostrando ítems 1-10 de 325
Hypusine modification of the ribosome-binding protein eIF5A, a target for new anti-inflammatory drugs: Understanding the action of the inhibitor GC7 on a murine macrophage cell line
(2014-01-30)
Inflammation is part of an important mechanism triggered by the innate immune response that rapidly responds to invading microorganisms and tissue injury. One important elicitor of the inflammatory response is the Gram-negative ...
Anti-TNF and postoperative complications in abdominal crohn's disease surgery
(2019-01-01)
Background: Biological therapy with anti-Tumour Necrosis Factor (TNF)-α agents revolutionised the treatment of inflammatory bowel disease over the last decades. However, there may be an increased risk of postoperative ...
Label-Free Quantification of Anti-TNF-α in Patients Treated with Adalimumab Using an Optical Biosensor
(Sensors (Basel), 2018-02-26)
This study describes the development of an immunosensory label-free quantification methodology based on surface plasmon resonance (SPR) and its applicability in measuring/evaluating therapeutic drug monitoring (TDM) of ...
Small Molecules as Anti-TNF Drugs
(Bentham Science Publishers, 2015)
Tumor necrosis factor (TNF, TNF-α, cachectin) is a pleiotropic, proinflammatory cytokine with multiple biological effects, many of which are not yet fully understood. Although TNF was initially described as an anti-tumor ...
Anti-inflammatory activity of Lychnophora passerina, Asteraceae (Brazilian arnica)
(2011-05-17)
Ethnopharmacological relevance: Lychnophora passerina (Asteraceae), popularly known as arnica, is used to treat inflammation, pain, rheumatism, contusions, bruises and insect bites in Brazilian traditional medicine. Materials ...
Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis
(2016-09-01)
TNF-α is involved in the mechanisms that initiate inflammatory bowel diseases (IBDs). Anti-TNF-α drugs, such as infliximab (IFX), cause non-responsiveness and side effects, indicating the need to investigate alternative ...
Diazepam, em dose única, inibe a migração celular, a estimulação macrofágica e a atividade de TNF-α na reação inflamatória aguda induzida por LPS em camundongosDiazepam, in a single dose, inhibits cellular chemotaxis, macrophage stimulation, and TNF-α activity in LPS-induced acute inflammatory responses in mice
(Universidade de São Paulo (USP), Conjunto Quimicas, 2014)
Asociación y capacidad de predicción de los anticuerpos y de los niveles de medicamento anti-TNF α con la respuesta clínica en pacientes con Artritis Reumatoide y Espondiloartritis tratados con Biológicos anti-TNF en Hospital Militar Central.
Objetivo: Evaluar asociación y la capacidad de predicción de los niveles de medicamento anti-TNF α y de anticuerpos contra anti-TNF α con relación a la respuesta clínica en pacientes con Artritis Reumatoide (AR) y ...
Adult T-cell leukemia/lymphoma triggered by adalimumab
(2013)
Here, we describe a 48-year-old woman infected by the human T-cell lymphotropic virus type 1 (HTLV-1) with spondyloarthritis, uveitis, bilateral episcleritis and neurogenic bladder. She had a history of a probable infective ...