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Clinical parameters and biomarkers for anti-TNF treatment prognosis in rheumatoid arthritis patients
(International League of Associations for Rheumatology (ILAR), 2014)
Tumor necrosis factor (TNF) plays a pivotal role in
the pathogenesis of rheumatoid arthritis (RA). This finding
has led to the development of TNF blockers for RA treatment.
However, response to these therapies is ...
Efetividade clínica dos medicamentos biológicos anti-TNF, biológicos não anti-TNF e sintético alvo-específico no tratamento da artrite reumatoide.
(Universidade Federal de Minas GeraisBrasilFARMACIA - FACULDADE DE FARMACIAPrograma de Pós-Graduação em Medicamentos e Assistencia FarmaceuticaUFMG, 2022-02-24)
Introduction: Rheumatoid Arthritis is a systemic, chronical inflammatory disease
associated to peripheral polyarthritis, which leads to deformity and destruction of
joints due to erosion of cartilage and bone. Treatment ...
Anti-TNF and postoperative complications in abdominal crohn's disease surgery
(2019-01-01)
Background: Biological therapy with anti-Tumour Necrosis Factor (TNF)-α agents revolutionised the treatment of inflammatory bowel disease over the last decades. However, there may be an increased risk of postoperative ...
Anti-TNF Exposure during Pregnancy in Crohn's Disease Patients
(2018-09-01)
Inflammatory bowel disease (IBD) affects young people of reproductive age. Therefore, a broad discussion is needed about the possible disease effects in pregnancy, as well as the risks of fetal exposure to the medications ...
Small Molecules as Anti-TNF Drugs
(Bentham Science Publishers, 2015)
Tumor necrosis factor (TNF, TNF-α, cachectin) is a pleiotropic, proinflammatory cytokine with multiple biological effects, many of which are not yet fully understood. Although TNF was initially described as an anti-tumor ...