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Isoflavone genistein inhibits the angiotensin-converting enzyme and alters the vascular responses to angiotensin I and bradykinin
(ELSEVIER SCIENCE BV, 2009)
Genistein produces antihypertensive and beneficial cardiovascular effects, although the mechanisms for these effects are not known. We examined whether genistein inhibits the in vivo responses to angiotensin I or enhances ...
Renin-angiotensin system blockers and severe acute respiratory syndrome coronavirus 2
Severe acute respiratory syndrome coronavirus 2, which is responsible for the current coronavirus
disease 2019 pandemic, uses angiotensin-converting enzyme 2 as a gateway into host cells. In this
review, we summarize the ...
Increased Expression of Angiotensin II Type 2 Receptors in the Solitary-Vagal Complex Blunts Renovascular Hypertension
(Lippincott Williams & Wilkins, 2014-10-01)
Angiotensin II increases and decreases arterial pressure by acting at angiotensin type 1 and type 2 receptors, respectively. Renovascular hypertensive rats exhibit a high level of activity of the peripheral and central ...
PINDOLOL Df,CREASES PLASMA ANGIOTENSIN-CONVERTING ENZYME ACTIVITY IN YOUNG SPONTANEOUSLY HYPERTTNSIVE RATS
(European Journal ol Pharmocolog/,, 2011)
Levels of plasma angiotensin-(1-7) in patients with hypertension who have the angiotensin-1-converting enzyme deletion/deletion genotype
(EXCERPTA MEDICA INC, 2003-09-15)
In patients with hypertension who have the DD-ACE genotype (higher angiotensin-converting enzyme [ACE] activity), plasma levels of angiotensin-(1-7) are 4 times lower than in patients with the II-ACE genotype (lower ACE ...
Increased aortic NADPH oxidase activity in rats with genetically high angiotensin-converting enzyme levels
(LIPPINCOTT WILLIAMS & WILKINS, 2005-12)
In humans and rats, angiotensin I-converting enzyme activity is significantly determined by a gene polymorphism. Homozygous Brown Norway rats have higher plasma angiotensin I-converting enzyme activity and circulating ...
Rho kinase activation and gene expression related to vascular remodeling in normotensive rats with high angiotensin I-converting enzyme levels
(2007)
The RhoA/Rho kinase (ROCK) pathway is a new mechanism of remodeling and vasoconstriction. Few data are available regarding ROCK activation when angiotensin I-converting enzyme is high and blood pressure is normal. We ...
Prevalence of the angiotensin I converting enzyme insertion deletion polymorphism, plasma angiotensin converting enzyme activity, and left ventricular mass in a normotensive Chilean population
(ELSEVIER SCIENCE INC, 1999)
The aim of this study was to estimate the prevalence of the different alleles of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and associated plasma ACE activity, as well as cardiac ...
Prevalence of the angiotensin I converting enzyme insertion/deletion polymorphism, plasma angiotensin converting enzyme activity, and left ventricular mass in a normotensive Chilean population
(1999)
The aim of this study was to estimate the prevalence of the different alleles of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and associated plasma ACE activity, as well as cardiac ...