Now showing items 1-10 of 435
Inhibition of beta-amyloid Aggregation of Ugni molinae Extracts
(Bentham Science Publishers, 2020)
The beta-amyloid peptide (1-42) is a molecule capable of aggregating into neurotoxic structures that have been implicated as potential etiological factors of Alzheimer's Disease. The aim of this study was to evaluate the ...
Gold Nanoparticles as Nucleation Centers for Amyloid Fibrillation
The aggregation of proteins into amyloid fbrils is related to more than 30 diseases, including the most common neurodegenerative conditions. Amyloid fbrillation is a nucleation-dependent polymerization reaction where ...
Small Molecule Inhibitors of Lysozyme Amyloid Aggregation
Albumin-induced circular dichroism in Congo red: applications for studies of amyloid-like fibril aggregates and binding sites
(Elsevier B. V., 2015-11-05)
Congo red (CR), one of the most commonly used dyes for the identification of amyloid fibril aggregates, is also a ligand of native bovine serum albumin (BSA). Induced circular dichroism (ICD) is a phenomenon observed when ...
Amyloid Precursor Protein in Central and Peripheral Cholinergic Synaptopathies
(Nova Science Publishers, 2011-05)
Alzheimer´s disease is the most widespread form of dementia in the elderly. One of the characteristics of this disease is the profound functional deficit of the cholinergic system as a consequence of synaptic loss. Amyloid ...