Chronic exposure to Cannabis sativa (marijuana) produced a significant down-regulation of cannabinoid receptor in the postmortem human brain. the significant decrease in maximal binding capacity was not accompanied by ...

Acute global cerebral ischemia triggers pathophysiological phenomena leading to death of vulnerable neurons in specific brain structures (pyramidal neurons of the Ammon’s horn and layers III and V of the prefrontal cortex) ...

Permanent reduction of cerebral blood flow (chronic cerebral hypoperfusion, CCH), aging, and a reduction of estrogenic actions, have been considered as concurrent conditions able to induce damage to brain structures such ...

The present report summarizes studies combining an in vivo and in vitro approach, where asphyxia is induced in vivo at delivery time of Wistar rats, and the long term effects on hippocampus neurocircultry are investigated ...

Myosin Va is an actin-based, processive molecular motor protein highly enriched in the nervous tissue of vertebrates. It has been associated with processes of cellular motility, which include organelle transport and neurite ...

The prefrontal cortex is continuously required for working memory processing during wakefulness, but is particularly hypoactivated during sleep and in psychiatric disorders such as schizophrenia. Ammon`s horn CA1 hippocampus ...

The tissue sclerosis found in epilepsy of limbic origin is characterized by shrunken gliotic hippocampus, granule cell loss in the dentate gyrus and extensive pyramidal cell loss in Ammon's horn. Evidence has indicated ...

Neurological deficits in the offspring caused by human maternal hypothyroxinemia are thought to be irreversible. To understand the mechanism responsible for these neurological alterations, we induced maternal hypothyroxinemia ...