Buscar
Mostrando ítems 1-10 de 505
Thousands of protein linear motif classes may still be undiscovered
(Public Library of Science, 2021-05-03)
Linear motifs are short protein subsequences that mediate protein interactions. Hundreds of motif classes including thousands of motif instances are known. Our theory estimates how many motif classes remain undiscovered. ...
The ferric iron uptake regulator (Fur) from the extreme acidophile Acidithiobacillus ferrooxidans
(Microbiology Society, 2005-06)
Acidithiobacillus ferrooxidans is a Gram-negative bacterium that lives at pH 2 in high concentrations of soluble ferrous and ferric iron, making it an interesting model for understanding the biological mechanisms of bacterial ...
Computational prediction of short linear motifs from protein sequences
(Springer, 2015-01)
Short Linear Motifs (SLiMs) are functional protein microdomains that typically mediate interactions between a short linear region in one protein and a globular domain in another. SLiMs usually occur in structurally disordered ...
Characterization and analysis of conserved motifs in a peroxisomal ATP-binding cassette transporter
(The American Society forBiochemistry and Molecular Biology, Inc., 1996)
The adrenoleukodystrophy protein (ALDP) and the 70-kDa peroxisomal membrane protein are half ATP-binding cassette (ABC) transporters in the human peroxisome membrane. Both are implicated in genetic disorders of peroxisome ...
Cholesterol-recognizing amino acid consensus motifs in transmembrane proteins: Comparative analysis of in silico studies and structural data
(Academic Press, 2022)
Cholesterol binding to proteins is a dynamic process that involves a combination of geometric, biochemical, and biophysical principles. These properties can be viewed as basic rules which govern any kind of molecular ...
Antibodies to yeast Sm motif 1 cross-react with human Sm core polypeptides
(Blackwell Science, 1999-04-01)
Two regions common to all UsnRNP core polypeptides have been described: Sm motif 1 and Sm motif 2. Rabbits were immunized with a 22 amino-acid peptide containing one segment of Sm motif 1 (YRGTLVSTDNYFNLQL-NEAEEF, corresponding ...
Antibodies to yeast Sm motif 1 cross-react with human Sm core polypeptides
(Blackwell Science, 1999-04-01)
Two regions common to all UsnRNP core polypeptides have been described: Sm motif 1 and Sm motif 2. Rabbits were immunized with a 22 amino-acid peptide containing one segment of Sm motif 1 (YRGTLVSTDNYFNLQL-NEAEEF, corresponding ...
A SequenceSpace analysis of Lys49 phospholipases A2: Clues towards identification of residues involved in a novel mechanism of membrane damage and in myotoxicity
(1998-04-01)
'SequenceSpace' analysis is a novel approach which has been used to identify unique amino acids within a subfamily of phospholipases A2 (PLA2) in which the highly conserved active site residue Asp49 is substituted by Lys ...