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Self-declared ethnicity and genomic ancestry in prostate cancer patients from Brazil
(Funpec-editora, 2016-01-01)
Some studies of polymorphisms in prostate cancer (PCa) analyze individuals in a uniform manner, regardless of genetic ancestry. However, PCa aggressiveness differs between subjects of African descent and those of European ...
Amerindian ancestry and extended longevity in Nicoya, Costa Rica
(2018-01)
Objectives: The aim of this study was to address the hypothesis that Amerindian
ancestry is associated with extended longevity in the admixed population of Nicoya,
Costa Rica. The Nicoya Peninsula of Costa Rica has been ...
Amerindian ancestry and extended longevity in Nicoya, Costa Rica
(2018-01)
Objectives: The aim of this study was to address the hypothesis that Amerindian
ancestry is associated with extended longevity in the admixed population of Nicoya,
Costa Rica. The Nicoya Peninsula of Costa Rica has been ...
Dissecting the role of Amerindian genetic ancestry and the ApoE ε4 allele on Alzheimer disease in an admixed Peruvian population
(Elsevier, 2021)
Alzheimer disease (AD) is the leading cause of dementia in the elderly and occurs in all ethnic and racial groups. The apolipoprotein E (ApoE) ε4 is the most significant genetic risk factor for late-onset AD and shows the ...
Neither self-reported ethnicity nor declared family origin are reliable indicators of genomic ancestry
(2016-06-01)
Ancestry information can be useful in investigations of diseases with a genetic or infectious background. As the Brazilian population is highly admixed physical traits tend to be poor indicators of ancestry. The assessment ...
Amerindian admixture estimation based on serological and molecular methods Estimadores de mezcla Amerindia basados en métodos serológicos y moleculares
(Sociedad Medica de Santiago, 2015)
© 2015, Sociedad Medica de Santiago. All rights reserved. Background: Amerindian admixture is an important parameter to consider in epidemiological studies in American countries, to make a proper selection of cases and ...
Ancestry informative markers in Amerindians from Brazilian Amazon
(WILEY-LISS, 2008)
Ancestry informative markers (AIMs) are genetic loci with large frequency differences between the major ethnic groups and are very useful in admixture estimation. However, their frequencies are poorly known within South ...
A systematic literature review on the European, African and Amerindian genetic ancestry components on Brazilian health outcomes
(2019-12-01)
The variables such as race, skin colour and ethnicity have become intensely discussed in medicine research, as a response to the rising debate over the importance of the ethnic-racial dimension in the scope of health-disease ...
Effect of 15 BMI-Associated polymorphisms, reported for europeans, across ethnicities and degrees of amerindian ancestry in mexican children
(MDPI, 2020)
In Mexico, the genetic mechanisms underlying childhood obesity are poorly known. We evaluated the effect of loci, known to be associated with childhood body mass index (BMI) in Europeans, in Mexican children from different ...
Development of a small panel of SNPs to infer ancestry in chileans that distinguishes Aymara and Mapuche components
(Sociedad de Biología de Chile, 2020)
Background Current South American populations trace their origins mainly to three continental ancestries, i.e. European, Amerindian and African. Individual variation in relative proportions of each of these ancestries may ...