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The Genetic Diversity of the Americas
(Annual Reviews, 2017)
The history of the Americas involved the encounter of millions of Native Americans, Europeans, and Africans. A variable admixture of these three continental groups has taken place throughout the continent, influenced by ...
Geografía génica de Chile. Distribución regional de los aportes genéticos americanos, europeos y africanos
(Sociedad Médica de Santiago, 2014)
Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African). Aim: To estimate the regional rate ...
Development of a panel of genome-wide ancestry informative markers to study admixture throughout the americas
(Public Library of Science, 2012)
Most individuals throughout the Americas are admixed descendants of Native American, European, and African ancestors. Complex historical factors have resulted in varying proportions of ancestral contributions between ...
Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance
(Springer Nature, 2018)
Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, ...
Genomic ancestry, CYP2D6, CYP2C9 and CYP2C19 among Latin-Americans
(Wiley, 2019)
We present the distribution of CYP2D6, CYP2C9 and CYP2C19 variants and predicted phenotypes in 33 native and admixed populations from Ibero-America (n>6,000) in the context of genetic ancestry (n=3,387). Continental ...
Geografía génica de Chile. Distribución regional de los aportes genéticos americanos, europeos y africanos
(Sociedad Médica de Santiago, 2014)
Background: The geographical distribution of genes plays a key role in genetic epidemiology. The Chilean population has three major stem groups (Native American, European and African)…
A genome-wide association study identifies multiple loci for variation in human ear morphology
(Springer Nature, 2015)
Here we report a genome-wide association study for non-pathological pinna morphology in over 5,000 Latin Americans. We find genome-wide significant association at seven genomic regions affecting: lobe size and attachment, ...
Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations
(National Academy of Sciences, 2015)
While South Americans are underrepresented in human genomic diversity studies, Brazil has been a classical model for population genetics studies on admixture.We present the results of the EPIGEN Brazil Initiative, the most ...
Amerindian admixture estimation based on serological and molecular methods Estimadores de mezcla Amerindia basados en métodos serológicos y moleculares
(Sociedad Medica de Santiago, 2015)
© 2015, Sociedad Medica de Santiago. All rights reserved. Background: Amerindian admixture is an important parameter to consider in epidemiological studies in American countries, to make a proper selection of cases and ...