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Rhythmic behavior is controlled by the SRm160 splicing factor in Drosophila melanogaster
(Genetics Society of America, 2017-10)
Circadian clocks organize the metabolism, physiology, and behavior of organisms throughout the day–night cycle by controlling daily rhythms in gene expression at the transcriptional and post-transcriptional levels. While ...
The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators
(Oxford University Press, 2016-10-17)
Alternative splicing (AS) is a key component of gene expression programs that drive cellular differentiation. Smooth muscle cells (SMCs) are important in the function of a number of physiological systems; however, investigation ...
ASpli: integrative analysis of splicing landscapes through RNA-Seq assays
(Oxford University Press, 2021-03)
Genome-wide analysis of alternative splicing has been a very active field of research since the early days of Next Generation Sequencing technologies. Since then, ever-growing data availability and the development of ...
Differential splicing analysis based on isoforms expression with NBSplice
(Academic Press Inc Elsevier Science, 2020-03)
Alternative splicing alterations have been widely related to several human diseases revealing the importance of their study for the success of translational medicine. Differential splicing (DS) occurrence has been mainly ...
Splicing regulators and their roles in cancer biology and therapy
(BioMed Research International, 2017)
Characterization of a multicopper oxidase gene cluster in phanerochaete chrysosporium and evidence of altered splicing of the mco transcripts
(SOCIETY FOR GENERAL MICROBIOLOGY, 2004)
Incomplete processing of peroxidase transcripts in the lignin degrading fungus Phanerochaete chrysosporium
(2005)
Phanerochaete chrysosporium has been thoroughly studied as a microbial model for lignin degradation. The enzymes lignin peroxidase (LiP) and manganese peroxidase (MnP), both encoded by several genes, play the main role in ...
Innovative Therapeutic and Delivery Approaches Using Nanotechnology to Correct Splicing Defects Underlying Disease
(Frontiers Media, 2020-07)
Alternative splicing of pre-mRNA contributes strongly to the diversity of cell- and tissue-specific protein expression patterns. Global transcriptome analyses have suggested that >90% of human multiexon genes are alternatively ...