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alpha(1)-Adrenoceptors in proximal segments of tail arteries from control and reserpinised rats
(Springer, 2007-10-01)
It has been recently shown that the supersensitivity of distal segments of the rat tail artery to phenylephrine after chemical sympathectomy with reserpine results from the appearance of alpha(1D)-adrenoceptors. It is known ...
alpha(1)-Adrenoceptors in proximal segments of tail arteries from control and reserpinised rats
(Springer, 2007-10-01)
It has been recently shown that the supersensitivity of distal segments of the rat tail artery to phenylephrine after chemical sympathectomy with reserpine results from the appearance of alpha(1D)-adrenoceptors. It is known ...
The affinity and selectivity of alpha-adrenoceptor antagonists, antidepressants, and antipsychotics for the human alpha 1A, alpha 1B, and alpha 1D-adrenoceptors
(Wiley-Blackwell, 2020-08-01)
alpha 1-adrenoceptor antagonists are widely used for hypertension (eg, doxazosin) and benign prostatic hypertrophy (BPH, eg, tamsulosin). Some antidepressants and antipsychotics have been reported to have alpha 1 affinity. ...
The tricyclic antidepressants amitriptyline, nortriptyline and imipramine are weak antagonists of human and rat alpha(1B)-adrenoceptors
(Pergamon-Elsevier B.V. Ltd, 2010-07-01)
Although it is long known that the tricyclic antidepressants amitriptyline, nortriptyline and imipramine inhibit the noradrenaline transporter and alpha(1)-adrenoceptors with similar affinities, which may lead to self-cancelling ...
The tricyclic antidepressants amitriptyline, nortriptyline and imipramine are weak antagonists of human and rat alpha(1B)-adrenoceptors
(Pergamon-Elsevier B.V. Ltd, 2010-07-01)
Although it is long known that the tricyclic antidepressants amitriptyline, nortriptyline and imipramine inhibit the noradrenaline transporter and alpha(1)-adrenoceptors with similar affinities, which may lead to self-cancelling ...
Both alpha 1 and alpha 2-adrenoceptors mediate the cardiovascular responses to noradrenaline microinjected into the bed nucleus of the stria terminal of rats
(NATURE PUBLISHING GROUP, 2008)
Background and purpose: We have previously shown that noradrenaline microinjected into the bed nucleus of stria terminalis (BST) elicited pressor and bradycardiac responses in unanaesthetized rats. In the present study, ...
Involvement of alpha(1B)-adrenoceptors in the anti-immobility effect of imipramine in the tail suspension test
(Elsevier B.V., 2015-03-05)
Imipramine is a tricyclic antidepressant inhibitor of norepinephrine and serotonin neuronal reuptake. The roles of specific alpha(1)-adrenoceptor subtypes that might be targeted by the increased synaptic levels of noradrenaline ...
Effects of castration on alpha(1)-adrenoceptor subtypes in the rat aorta
(Elsevier B.V., 2002-12-01)
The expression of alpha(1)-adrenoceptor subtypes in several tissues is regulated by gonadal hormones. In this study, we investigated whether castration regulates the alpha(1)-adrenoceptor subtypes mediating the contractions ...
Effects of castration on alpha(1)-adrenoceptor subtypes in the rat aorta
(Elsevier B.V., 2002-12-01)
The expression of alpha(1)-adrenoceptor subtypes in several tissues is regulated by gonadal hormones. In this study, we investigated whether castration regulates the alpha(1)-adrenoceptor subtypes mediating the contractions ...
Activation of alpha(2)-adrenoceptors in the lateral hypothalamus reduces pilocarpine-induced salivation in rats
(Elsevier B.V., 2009-02-06)
Anti-hypertensive drugs that act oil central alpha(2)-adrenoceptors and imidazoline receptors usually cause dry mouth in patients. A central area important for the control of salivary secretion and also for the effects of ...