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New PPAR alpha/gamma/delta Optimal Activator Rationally Designed by Computational Methods
(Soc Brasileira Quimica, 2016-09-01)
The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor that acts as a transcription factor, regulating glucose, lipid and inflammation signaling and it is exploited in type 2 diabetes ...
Molecular Mechanism of Peroxisome Proliferator-Activated Receptor alpha Activation by WY14643: a New Mode of Ligand Recognition and Receptor Stabilization
(Academic Press Ltd- Elsevier Science LtdLondonInglaterra, 2013)
A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis
(WILEY, 2008)
Peroxisome proliferator activated receptors (PPARs, alpha, beta/delta, gamma) control lipid homeostasis and differentiation in various tissues and tumor cells. PPAR beta and PPAR gamma increase oligodendrocyte maturation ...
Megalin/LRP2 Expression Is Induced by Peroxisome Proliferator-Activated Receptor -Alpha and -Gamma: Implications for PPARs' Roles in Renal Function
(PUBLIC LIBRARY SCIENCE, 2011)
Background: Megalin is a large endocytic receptor with relevant functions during development and adult life. It is expressed at the apical surface of several epithelial cell types, including proximal tubule cells (PTCs) ...
Mode of Peroxisome Proliferator-Activated Receptor gamma Activation by Luteolin
(AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICSBETHESDA, 2012)
The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a target for treatment of type II diabetes and other conditions. PPAR gamma full agonists, such as thiazolidinediones (TZDs), are effective insulin ...
Mode of Peroxisome Proliferator-Activated Receptor gamma Activation by Luteolin
(Amer Soc Pharmacology Experimental Therapeutics, 2012-06-01)
The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a target for treatment of type II diabetes and other conditions. PPAR gamma full agonists, such as thiazolidinediones (TZDs), are effective insulin ...
Mode of Peroxisome Proliferator-Activated Receptor gamma Activation by Luteolin
(Amer Soc Pharmacology Experimental Therapeutics, 2012-06-01)
The peroxisome proliferator-activated receptor gamma (PPAR gamma) is a target for treatment of type II diabetes and other conditions. PPAR gamma full agonists, such as thiazolidinediones (TZDs), are effective insulin ...