Buscar
Mostrando ítems 1-10 de 143
Structure- and Ligand-Based Structure-Activity Relationships for a Series of Inhibitors of Aldolase
(BENTHAM SCIENCE PUBL LTDSHARJAH, 2012)
Aldolase has emerged as a promising molecular target for the treatment of human African trypanosomiasis. Over the last years, due to the increasing number of patients infected with Trypanosoma brucei, there is an urgent ...
In guinea pig sperm, aldolase A forms a complex with actin, WAS, and Arp2/3 that plays a role in actin polymerization
(2009)
Glycolytic enzymes have, in addition to their role in energy production, other functions in the regulation of cellular processes. Aldolase A has been reported to be present in sperm, playing a key role in glycolysis; ...
Effect of lysine acetylation on the regulation of Trypanosoma brucei glycosomal aldolase activity
(Portland Press, 2020)
Post-translational modifications provide suitable mechanisms for cellular adaptation to environmental changes. Lysine acetylation is one of these modifications and occurs with the addition of an acetyl group to Nε-amino ...
Glucose Metabolism in Escherichia coli and the Effect of Increased Amount of Aldolase
(1993)
We present a comparative study of Escherichia coli with normal and increased amounts of fructose-1,6-bisphosphate aldolase. Most experiments employed a resting cell system involving a high cell density (so as to obtain the ...
Importancia de las aldolasas en la síntesis de productos anticolesterolémicosAldolases : useful enzymes for the synthesis of anticholesterolemic products
(Secretaría de Posgrado. Universidad Nacional de Quilmes, 2019-05-30)
Las aldolasas – enzimas pertenecientes al grupo de las liasas – son biocatalizadores efectivos para realizar reacciones de adición aldólica en medios acuosos, con elevado rendimiento y alta estereoselectividad. Según el ...
Effect of lysine acetylation on the regulation of Trypanosoma brucei glycosomal aldolase activity
(2020-05-01)
Post-translational modifications provide suitable mechanisms for cellular adaptation to environmental changes. Lysine acetylation is one of these modifications and occurs with the addition of an acetyl group to Nϵ-amino ...
N-Acetylneuraminic acid aldolase-catalyzed synthesis of acyclic nucleoside analogues carrying a 4-hydroxy-2-oxoacid moiety
(Elsevier Science, 2019-03)
N-Acetylneuraminic acid aldolase (NeuAcA) (EC 4.1.3.3) is a pyruvate-dependent class I aldolase that catalyzes the reversible aldol cleavage of N-acetylneuraminic acid to form N-acetyl-D-mannosamine and pyruvate. The ...