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Increase in distal airway mucus-producing Clara cells during primary Pneumocystis infection
(2018)
Airway Clara cells exhibit plasticity and may differentiate into goblet cells that
secrete mucus under different stimuli. Mucus originating in transformed Clara
cells along distal and alveolar duct airways that normally ...
Notch signaling controls the balance of ciliated and secretory cell fates in developing airways
(COMPANY OF BIOLOGISTS LTD, 2009)
Although there is accumulated evidence of a role for Notch in the developing lung, it is still unclear how disruption of Notch signaling affects lung progenitor cell fate and differentiation events in the airway epithelium. ...
Current strategies and opportunities to manufacture cells for modeling human lungs
Chronic lung diseases remain major healthcare burdens, for which the only curative treatment is
lung transplantation. In vitro human models are promising platforms for identifying and testing
novel compounds to potentially ...
Differential regulation of the release of tumor necrosis factor-alpha and of eicosanoids by mast cells in rat airways after antigen challenge
(Carfax Publishing, 2003-08-01)
Background: Rat trachea display a differential topographical distribution of connective tissue mast cells (CTMC) and mucosal mast cells (MMC) that may imply regional differences in the release of allergic mediators such ...
Differential regulation of the release of tumor necrosis factor-alpha and of eicosanoids by mast cells in rat airways after antigen challenge
(Carfax Publishing, 2003-08-01)
Background: Rat trachea display a differential topographical distribution of connective tissue mast cells (CTMC) and mucosal mast cells (MMC) that may imply regional differences in the release of allergic mediators such ...
Differential regulation of the release of tumor necrosis factor-alpha and of eicosanoids by mast cells in rat airways after antigen challenge
(Carfax Publishing, 2003-08-01)
Background: Rat trachea display a differential topographical distribution of connective tissue mast cells (CTMC) and mucosal mast cells (MMC) that may imply regional differences in the release of allergic mediators such ...
Inhibition of the sodium-dependent HCO3 - transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype
(2022-05)
Bicarbonate secretion is a fundamental process involved in maintaining acid-base homeostasis. Disruption of bicarbonate entry into airway lumen, as has been observed in cystic fibrosis, produces several defects in lung ...
Creatine Activates Airway Epithelium in Asthma
(GEORG THIEME VERLAG KG, 2010)
Airway epithelium plays important roles in the pathophysiology of asthma. Creatine supplementation (Cr) was shown to increase asthma features in a murine model of allergic asthma; however, the role of the airway epithelium ...