Natural β-folds manage to fold up successfully. By contrast, attempts to dissect fragments or peptides from well folded β-sheet proteins have met with insurmountable difficulties. Here we briefly review selected successful ...

Δ98Δ is a functional all-β sheet variant of intestinal fatty acid binding protein (IFABP) that was generated by controlled proteolysis. This framework is useful to study the molecular determinants related to aggregation ...

A clear understanding of the structural foundations underlying protein aggregation is an elusive goal of central biomedical importance. A step toward this aim is exemplified by the β- barrel motif represented by the ...

Neuronal activity loss may be due to toxicity caused by amyloid-beta peptides forming soluble oligomers. Here amyloid-beta peptides (1–42, 1–40, 1–39, 1–38, and 1–37) are characterized through the modeling of their ...

This paper explores the potential for manufacturing internally cured concretes with lightweight aggregate (LWA) that has different initial moisture contents prior to mixing: oven-dry, 24 h pre-wetted, and vacuum saturated. ...

This paper proposes a simple alternative for the treatment e ect estimators based on match- ing on the estimated propensity score. In this approach, both weights and the number of coun- terfactuals employed in realizing ...