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Postsynaptic recordings at afferent dendrites contacting cochlear inner hair cells: Monitoring multivesicular release at a ribbon synapse
(Journal of Visualized Experiments, 2011-02)
The afferent synapse between the inner hair cell (IHC) and the auditory nerve fiber provides an electrophysiologically accessible site for recording the postsynaptic activity of a single ribbon synapse. Ribbon synapses of ...
Synaptic contacts established by inferior alveolar nerve fibres in the paratrigeminal nucleus: an electron microscopic study in the rat
(Elsevier B.V., 2005-01-01)
A quantitative evaluation of the types of synaptic contacts from afferent fibres in the paratrigerminal nucleus after partial pulpectomy was compared with that after transection of the inferior alveolar nerve (IAN), using ...
Cochlear hair cells: The sound-sensing machines
(Elsevier, 2015-08-31)
The sensory epithelium of the mammalian inner ear contains two types of mechanosensory cells:inner (IHC) and outer hair cells (OHC). They both transduce mechanical force generated by soundwaves into electrical signals. In ...
A comparative and ultrastructural study of synaptic contacts established by primary sensory fibers in the spinal trigeminal nucleus of the rat
(1996-01-01)
A quantitative evaluation of the types of afferent synaptic contacts in the pars oralis, using transganglionic degeneration and a comparison of previous data obtained from the pars interpolaris of the rat was performed. ...
Chronic Intermittent Hypoxia Depresses Afferent Neurotransmission in NTS Neurons by a Reduction in the Number of Active Synapses
(SOC NEUROSCIENCEWASHINGTON, 2012)
Long-term synaptic plasticity has been recently described in brainstem areas associated to visceral afferent sensory integration. Chronic intermittent hypoxia (CIH), an animal model for studying obstructive sleep apnea in ...
Activity-dependent regulation of the gabaergic synapse
(Universidad de Valparaíso, 2021)
ABSTRACT:
Excitatory and inhibitory balance play a fundamental role in regulation and maintenance of cerebral activity. Inhibitory regulation occurs by the action of diverse GABAergic cells that show activity-dependent ...
Encoding sound in the cochlea: from receptor potential to afferent discharge
(Wiley Blackwell Publishing, Inc, 2021-05)
Ribbon-class synapses in the ear achieve analog to digital transformation of a continuously graded membrane potential to all-or-none spikes. In mammals, several auditory nerve fibres (ANFs) carry information from each inner ...
The Cholinergic Lateral Line Efferent Synapse: Structural, Functional and Molecular Similarities With Those of the Cochlea
(Frontiers Media, 2021-10)
Vertebrate hair cell (HC) systems are innervated by efferent fibers that modulate their response to external stimuli. In mammals, the best studied efferent-HC synapse, the cholinergic medial olivocochlear (MOC) efferent ...
The role of the paratrigeminal nucleus in the pressor response to sciatic nerve stimulation in the rat
(Elsevier B.V., 2008-06-01)
The paratrigeminal nucleus (Pa5), an input site for spinal, trigeminal, vagus and glossopharyngeal afferents, is a recognized site for orofacial nociceptive sensory processing. It has efferent connections to brain structures ...
Synaptic contributions to cochlear outer hair cell Ca2+ dynamics
(Society for Neuroscience, 2021-08)
For normal cochlear function, outer hair cells (OHCs) require a precise control of intracellular Ca21 levels. In the absence of regulatory elements such as proteinaceous buffers or extrusion pumps, OHCs degenerate, leading ...