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Adjustments in β-adrenergic signaling contribute to the amelioration of cardiac dysfunction by exercise training in supravalvular aortic stenosis
(2020-01-01)
Background/Aims: Aortic stenosis-induced chronic pressure overload leads to cardiac dysfunction and congestive heart failure. The pathophysiological mechanisms of the myocardial impairment are multifactorial and include ...
Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion
(2020-11-01)
Purpose: Beta-adrenergic signaling can influence cancer progression and the use of beta blockers as adjuvant drugs in oncologic patients has been suggested. However, the involvement of beta-adrenergic blockers in tumorigenesis ...
Effects of α and β-adrenergic signaling on innate immunity and Porphyromonas gingivalis virulence in an invertebrate model
(Taylo&Francis, 2022-09-19)
To investigate the role of adrenergic signaling (AS) in the host immune response and Porphyromonas gingivalis virulence, we compared norepinephrine (NE) and isoproterenol (ISO) responses in Galleria mellonella. P. gingivalis ...
Interaction between Serotoninergic-and beta-adrenergic Receptors Signaling Pathways in Rat Femoral Artery
(Arquivos Brasileiros CardiologiaRio De JaneiroBrasil, 2012)
Role of beta-adrenergic receptors and sirtuin signaling in the heart during aging, heart failure, and adaptation to stress
(Springer/Plenum Publishers, 2018)
In the heart, catecholamine effects occur by activation of beta-adrenergic receptors (beta-ARs), mainly the beta 1 (beta(1)-AR) and beta 2 (beta(2)-AR) subtypes, both of which couple to the Gs protein that activates the ...
Neurocognitive Disorders in Heart Failure: Novel Pathophysiological Mechanisms Underpinning Memory Loss and Learning Impairment
(SPRINGER, 2019)
Heart failure (HF) is a major public health issue affecting more than 26 million people worldwide. HF is the most common cardiovascular disease in elder population; and it is associated with neurocognitive function decline, ...
Interação entre as vias de sinalização de receptores serotoninérgicos e Β-adrenérgicos em artéria femoral de ratos
(2012-01-01)
Fundamento: A doença coronária tem sido amplamente estudada em pesquisas cardiovasculares. No entanto, pacientes com doença arterial periférica (DAP) têm piores resultados em comparação àqueles com doença arterial coronariana. ...