Background: The diagnosis of Parkinson's disease (PD) can be challenging early in the diseasecourse, when motor features are subtle. The objective of this study was to explore the diagnostic value ofcombining acute levodopa ...

The influence of dopaminergic replacement (DR) on gait in people with Parkinson's disease (PD) is well documented. However, little is known about the acute effects of dopamine on more complex locomotor tasks that require ...

Phase IIa randomized double-blind, placebo-controlled study of inhaled apomorphine as acute challenge for rescuing 'off' periods in patients with established Parkinson's disease

Introduction: The implementation of accepted clinical diagnostic criteria has improved the accuracy of a clinical diagnosis of Parkinson's disease (PD). Time frames of 3–10 years have been empirically proposed to reach a ...

Findings involving the acute benefits of textured insoles on gait in people with Parkinson's disease (PD) are still controversial. To our best acknowledge, the continuous use of textured insoles on gait in people with PD ...

Introduction: The implementation of accepted clinical diagnostic criteria has improved the accuracy of a clinical diagnosis of Parkinson’s disease (PD). Time frames of 3 to 10 years have been empirically proposed to reach ...