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Oral health in children with acute lymphoblastic leukaemia: before and after chemotherapy treatment
(2020)
© 2019, European Academy of Paediatric Dentistry. Aim: To evaluate changes in the oral health status of children under the age of 14 years with acute lymphoblastic leukaemia (ALL) attending a cancer centre before and after ...
Differential expression of HDAC3, HDAC7 and HDAC9 is associated with prognosis and survival in childhood acute lymphoblastic leukaemia
(WILEY-BLACKWELL PUBLISHING, INC, 2010)
Altered expression of histone deacetylases (HDACs) is a common feature in several human malignancies and may represent an interesting target for cancer treatment, including haematological malignancies. We evaluated the ...
Oral mucositis in acute lymphoblastic leukaemia: analysis of 169 paediatric patients
(WILEY-BLACKWELL, 2008)
Chemotherapy-induced oral mucositis is a frequent therapeutic challenge in cancer patients. The purpose of this retrospective study was to estimate the prevalence and risk factors of oral mucositis in 169 acute lymphoblastic ...
Influence of lysosomal protease sensitivity in the immunogenicity of the antitumor biopharmaceutical asparaginase
(2020-12-01)
L-asparaginase (ASNase) from Escherichia coli (EcAII) is used in the treatment of acute lymphoblastic leukaemia (ALL). EcAII activity in vivo has been described to be influenced by the human lysosomal proteases asparaginyl ...
Discordant clinical presentation and outcome in infant twins sharing a common clonal leukaemia
(1996)
We report the different presentation features and clinical outcome between two identical infant twins with acute lymphoblastic leukaemia with a shared clonal disease and MLL gene rearrangement. One twin relapsed and died, ...
The presence of CD56/CD16 in T-cell acute lymphoblastic leukaemia correlates with the expression of cytotoxic molecules and is associated with worse response to treatment
(WILEY-BLACKWELL PUBLISHING, INC, 2009)
Some cases of T-cell acute lymphoblastic leukaemia (ALL) express markers found in natural-killer (NK) cells, such as CD56 and CD16. Out of 84 T-cell ALL cases diagnosed at our Institution, CD56 and/or CD16 was detected in ...
Common B-cell acute lymphoblastic leukaemia in a 70-year-old woman presenting 2 years after carboplatin-taxane radiotherapy for endometrial cancer
(CANCER INTELLIGENCE LTD, 2019)
Therapy-related acute lymphoblastic leukaemia (t-ALL) is a poorly defined entity and is not featured in the World Health Organization classification as a distinct clinical entity from acute lymphoblastic leukaemia (ALL), ...