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Bacille Calmette Guérin (BCG) and new TB vaccines: specific, cross-myco‐ bacterial and off-target effects
The Bacille Calmette Guérin (BCG) vaccine was developed over a century ago and has become one of the most used vaccines without undergoing a modern vaccine development life cycle. Despite this, the vaccine has protected ...
Evaluation of the Mycobacterium tuberculosis cell wall lipid-induced response in individuals with pulmonary tuberculosis
(Sociedade Brasileira de Medicina Tropical, 2017)
Estudos in vitro de citotoxicidade, interação farmacológica e atividade intramacrofágica de compostos benzofuroxanos
(Universidade Estadual Paulista (Unesp), 2022-05-20)
O Mycobacterium tuberculosis (M. tb) é o agente etiológico da segunda doença
infecciosa mais mortal do mundo atualmente, a tuberculose (TB), perdendo apenas para a
COVID-19 nos últimos 2 anos. O tratamento da doença é ...
No impact of helminth coinfection in patients with smear positive tuberculosis on immunoglobulin levels using a novel method measuring Mycobacterium tuberculosis-specific antibodies.
(Springer, 2023)
Helminth/tuberculosis (TB)-coinfection can reduce cell-mediated immunity against Mycobacterium tuberculosis (Mtb) and increase disease severity, although the effects are highly helminth species dependent. Mtb have long ...
MPT64 patch test for the diagnosis of active pulmonary tuberculosis: a randomised controlled trial in Peru
(International Union Against Tuberculosis and Lung Disease, 2018)
SETTING: There remains a lack of effective and inexpensive diagnostic tools for active tuberculosis (TB) disease. Testing immune responses to proteins secreted by Mycobacterium tuberculosis, such as MPT64, may be a diagnostic ...
Patient Reported Delays in Seeking Treatment for Tuberculosis among Adult and Pediatric TB Patients and TB Patients Co-Infected with HIV in Lima, Peru: A Qualitative Study
(Frontiers Media, 2014)
INTRODUCTION: Tuberculosis (TB) remains a significant public health challenge worldwide, and particularly in Peru with one of the highest incidence rates in Latin America. TB patient behavior has a direct influence on ...
Prevalent tuberculosis (TB) at HIV diagnosis in Rio de Janeiro, Brazil: The TB/HIV in Rio (THRio) cohort
(Lippincott, Williams & Wilkins, 2019)
Diabetes mellitus among pulmonary tuberculosis patients from four TB-endemic countries: the TANDEM study
(Oxford University Press, 2019)
BACKGROUND: Diabetes mellitus (DM) increases the risk of active tuberculosis (TB) and worsens TB outcomes, putting TB control in jeopardy especially in TB endemic countries with rising DM prevalence rates. We assessed DM ...
Epidemiological aspects of tuberculosis in children and adolescents in Rio de Janeiro
(SOC BRASIL PEDIATRIARIO DE JANEIRO, RJ, 2012)
Objective: To describe the epidemiological aspects of childhood tuberculosis (TB) in a Brazilian reference hospital. Methods: This was a retrospective study (1999-2008) of 473 subjects (0-14 year olds) with confirmed TB, ...
Screening diabetes mellitus patients for pulmonary tuberculosis: a multisite study in Indonesia, Peru, Romania and South Africa
(Oxford University Press, 2021)
BACKGROUND: Diabetes mellitus (DM) patients are three times more likely to develop tuberculosis (TB) than the general population. Active TB screening in people with DM is part of a bidirectional approach. The aim of this ...