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Intestinal uptake and toxicity evaluation of acetazolamide and its multicomponent complexes with Hidroxypropyl-β-Cyclodextrin in rats

Mora, Maria Julia; Petiti, Juan Pablo; Longhi, Marcela Raquel; Torres, Alicia Ines; Granero, Gladys Ester (Elsevier Science, 2015-01)

Large oral doses of ACZ lower the intraocular pressure (IOP), but usually lead to a multitude of systemic side effects, including gastrointestinal upset. The present study was undertaken to evaluate the effect of ACZ on ...