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Acetaldehyde-reinforcing effects: differences in low-alcohol-drinking (UChA) and high-alcohol-drinking (UChB) rats
(PERGAMON-ELSEVIER SCIENCE L, 2003-08)
It has been suggested that acetaldehyde has a biphasic effect on voluntary alcohol consumption. At low brain concentration, it might exert reinforcing effects, whereas high acetaldehyde levels would be predominantly aversive. ...
Aversion to acetaldehyde: Differences in low-alcohol-drinking (UChA) and high-alcohol-drinking (UChB) rats
(2002)
We have previously found the existence of a relation between activity of the brain mitochondrial aldehyde dehydrogenase (ALDH2) and consumption of ethanol in rats of the low-alcohol-drinking (UChA) and the high-alcohol-drinking ...
Generation of acetate and production of ethyl lysine in the reaction of acetaldehyde plus albumin
(PERGAMON-ELSEVIER SCIENCE LTD, 1999)
We report that incubation of acetaldehyde with bovine serum albumin results in the generation of acetate in a reaction that is directly proportional to the levels of albumin and exponentially dependent on the concentration ...
The "first hit" toward alcohol reinforcement: Role of ethanol metabolites
(Blackwell Publishing Ltd, 2015)
Effect of diet and disulfiram on acetaldehyde blood levels after ethanol in UChA and UChB rats
(1993)
Acetaldehyde (AcH) levels in blood samples taken from different zones of the vascular system 2 h after a p.o. dose of ethanol (2.76 g/kg) were studied in UChA (low ethanol consumer) and UChB (high ethanol consumer) rats ...
Generation of acetate and production of ethyl lysine in the reaction of acetaldehyde plus albuminALCOHOLAlcohol
(PERGAMON-ELSEVIER SCIENCE LTD, 2017)
Gene specific modifications unravel ethanol and acetaldehyde actions
(FRONTIERS RESEARCH FOUNDATION, 2013-07-08)
Ethanol is metabolized into acetaldehyde mainly by the action of alcohol dehydrogenase in the liver, while mainly by the action of catalase in the brain. Aldehyde dehydrogenase-2 metabolizes acetaldehyde into acetate in ...
Atmospheric Levels of Formaldehyde and Acetaldehyde and their Relationship with the Vehicular Fleet Composition in Salvador, Bahia, Brazil
(1998-05)
The present work is concerned with the formaldehyde and acetaldehyde content in the gas-phase and their concentrations correlation, with the vehicular fleet, at several sites in Salvador, BA, Brazil. The samples were ...
Acetaldehyde accumulation in rat mammary tissue after an acute treatment with alcohol
(Wiley, 2007-06)
Previous studies reported the presence in rat mammary tissue of a cytosolic xanthine oxidoreductase pathway for the metabolism of alcohol to acetaldehyde and hydroxyl radicals and to the microsomal biotransformation of ...