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Function of the Abelson nonreceptor tyrosine kinase 1 during the myogenesis of muscular adult precursors
(2020)
La miogénesis y regeneración muscular han sido intensamente investigadas por distintos grupos
en los contextos de la biología celular y la biomedicina regenerativa. El músculo esquelético
posee una tremenda habilidad de ...
Imatinib derivatives as inhibitors of K562 cells in chronic myeloid leukemia
(Springer Verlag (Germany), 2018)
Los inhibidores quinasa reducen la proteína c-Abelson fosforilada (c-abl-p) inducida por el H2O2 en un modelo neuronal colinérgico: implicaciones en la enfermedad de Alzheimer
(Grupo de Neurociencias de AntioquiaMedellín - Colombia, 2023)
Estudos in sı́lico de proteı́nas alostéricas e sua interação com ligantes
(Universidade Federal de São CarlosUFSCarPrograma de Pós-Graduação em Física - PPGFCâmpus São Carlos, 2023-02-24)
Allosteric proteins are extremely important for the regulation of several functions in
the organism, such as the transport of molecules through the blood and cell membranes,
as well as the phosphorylation of other proteins. ...
Hyaluronan abrogates imatinib-induced senescence in chronic myeloid leukemia cell lines
(Nature Publishing Group, 2019-12)
Hyaluronan (HA) is the main glycosaminoglycan of the extracellular matrix. CD44 is the most important HA receptor, and both have been associated with poor prognosis in cancer. Chronic myeloid leukemia (CML) is characterized ...
MiR-125a-3p and miR-320b differentially expressed in patients with chronic myeloid leukemia treated with allogeneic hematopoietic stem cell transplantation and imatinib mesylate
(2021-10-01)
Chronic myeloid leukemia (CML), a hematopoietic neoplasm arising from the fusion of BCR (breakpoint cluster region) gene on chromosome 22 to the ABL (Abelson leukemia virus) gene on chromosome 9 (BCR-ABL1 oncogene), ...
Funciones opuestas de las quinasas ABL en polarización neuronal
(Universidad de Chile, 2020)
En las neuronas la segregación de los compartimentos axonal y dendrítico es clave para
el flujo vectorial de información. Por lo cual, el fenómeno de polarización neuronal es
esencial para el desarrollo y el correcto ...