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Characterization of azole resistance mechanisms in chilean clinical isolates of Candida albicans Caracterización de los mecanismos de resistencia a azoles en aislados clínicos chilenos de Candida albicans
(Sociedad Chilena de Infectologia, 2014)
© 2014 Sociedad Chilena de Infectologia. All rights reserved. Abstract Introduction: The commensal yeast Candida albicans, can cause superficial or systemic candidiasis in susceptible hosts. In Chile, azole antifungals are ...
2D chemometric studies of a series of azole derivatives active against fluconazole-resistant Cryptococcus gattii
(Brasil, 2013)
Despite advances in the development of antifungal drugs,there has been an upsurge of cryptococosis infections that poorly respond to fluconazole (first choice drug). Hence,it is paramount to investigate the chemical ...
The one health problem of azole resistance in Aspergillus fumigatus: current insights and future research agenda
Azole resistance is a concern for the management of diseases caused by Aspergillus fumigatus in humans. Azole fungicide use in the environment has been identified as a possible
cause for development of resistance, which ...
An azole tolerant endosomal trafficking mutant of Candida albicans is susceptible to azole treatment in a mouse model of vaginal candidiasis.
(Estados Unidos Antimicrobial Agents and Chemotherapy, 2017., 2019-09-24)
We recently reported that a Candida albicans endosomal trafficking mutant continues to grow after treatment with the azole antifungals. Herein, we report that the vps21Δ/Δ mutant does not have a survival advantage over ...
Azole resistance among clinical isolates of Aspergillus fumigatus in Lima-Peru
(Oxford University Press, 2019)
Azole resistance among Aspergillus fumigatus isolates, which is mainly related to mutations in the cyp51A gene, is a concern because it is rising, worldwide disseminated, and associated with treatment failure and death. ...
Effectiveness of chlorhexidine on the disinfection of complete dentures colonised with fluconazole-resistant Candida albicans: in vitro study
(Wiley-Blackwell, 2011-09-01)
This in vitro study evaluated different concentrations of chlorhexidine (CHX) solution on the disinfection of dentures colonised with a reference (ATCC 90028) and azole-resistant (R1, R2 e R3) strains of Candida albicans. ...
Aspergillus spp.: suscetibilidade aos antifúngicos isolados e em associação por diferentes metodologias e detecção de mecanismos de resistência a azólicos
(Universidade Federal de Santa MariaBrasilFarmacologiaUFSMPrograma de Pós-Graduação em Ciências FarmacêuticasCentro de Ciências da Saúde, 2018-01-19)
Aspergillosis is a group of diseases among the main causes of morbidity and mortality in immunosuppressed patients. Aspergillus fumigatus is the most common species that causes invasive and non-invasive aspergillosis in ...
Molecular confirmation of the linkage between the rhizopus oryzae CYP51A gene coding region and its intrinsic voriconazole and fluconazole resistance
(American Society for Microbiology, 2018-08)
Rhizopus oryzae is the most prevalent causative agent of mucormycosis, an increasingly reported opportunistic fungal infection. These Mucorales are intrinsically resistant to Candida- and Aspergillus-active antifungal azole ...