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Immunosuppression and malignant neoplasms: Risk-benefit assessment in patients with inflammatory bowel disease
(2020-01-01)
Objective: Adverse events of drug therapy Background: The treatment of inflammatory bowel disease aims to induce and maintain disease remission, avoid complica-tions, and restore quality of life. The treatments include the ...
Everolimus Versus Azathioprine in a Cyclosporine and Ketoconazole–Based Immunosuppressive Therapy in Kidney Transplant: 3-Year Follow-up of an Open-Label, Prospective, Cohort, Comparative Clinical Trial
(ELSEVIER, 2010)
In cyclosporine-based protocols, everolimus is more effective than azathioprine to reduce
acute rejection. Ketoconazole may reduce cyclosporine and everolimus requirements. We
compared kidney transplant patients treated ...
Everolimus Versus Azathioprine in a Cyclosporine and Ketoconazole-Based Immunosuppressive Therapy in Kidney Transplant: 3-Year Follow-up of an Open-Label, Prospective, Cohort, Comparative Clinical Trial
(2010)
In cyclosporine-based protocols, everolimus is more effective than azathioprine to reduce acute rejection. Ketoconazole may reduce cyclosporine and everolimus requirements. We compared kidney transplant patients treated ...
American Gastroenterological Association Institute Guideline on the Medical Management of Microscopic Colitis
(Elsevier, 2016)
This article has an accompanying continuing medical education activity on page e17. Learning Objective: Upon completion of this test, successful learners will be able to: (1) learn first-line treatment for the induction ...
Split-dose administration of thiopurine drugs: a novel and effective strategy for managing preferential 6-MMP metabolism
(WILEY-BLACKWELL, 2012)
Background Mercaptopurine and azathioprine (AZA) are efficacious in treating IBD. 6-tioguanine (6-TGN) levels correlate with therapeutic efficacy, whereas high 6-methylmercaptopurine (6-MMP) levels are associated with ...
Role of Azathioprine in steroid resistant non infectious ocular inflammatory diseases Eficacia de la azatioprina en la enfermedad ocular inflamatoria no infecciosa resistente a tratamiento esteroidal sistémico
(2007)
Background: Topical and systemic steroids are the first line of treatment of non infectious inflammatory ocular disease. Immunosuppresants are reserved as a second line treatment. Aim: To evaluate the role of Azathioprine ...
Influence of post-transplant immunosuppressive therapy on gastrointestinal transit using biomagnetic method: a pilot study
(Springer, 2015-01-01)
Background Immunosuppressive therapy after kidney transplant is necessary to prevent allograft rejection and it is the cause of several gastrointestinal (GI) disorders that have been scantily studied.Objectives This study ...
Treatment of neuromyelitis optica: an evidence based reviewTratamento da neuromielite óptica: uma revisão baseada em evidências
(Academia Brasileira de Neurologia - ABNEURO, 2012)
Neuromyelitis optica (NMO) is an inflammatory disease of the central nervous system characterized by severe optic neuritis and transverse myelitis, usually with a relapsing course. Aquaporin-4 antibody is positive in a ...
Fecal microbiota transplantation in refractory ulcerative colitis – a case report
(2019-02-01)
Studies comparing gut microbiota profiles of inflammatory bowel disease (IBD) patients have shown several changes in microbiota composition, with marked reduction of local biodiversity relative to that of healthy controls. ...