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AVPR1A Sequence Variation in Monogamous Owl Monkeys (Aotus azarai) and Its Implications for the Evolution of Platyrrhine Social Behavior
(Springer, 2010-09)
The arginine vasopressin V1a receptor gene (AVPR1A) has been implicated in increased partner preference and pair bonding behavior in mammalian lineages. This observation is of considerable importance for studies of social ...
Evolução molecular dos receptores da oxitocina e da vasopressina em animais domesticados e de interesse comercialMolecular evolution of oxytocin and vasopressin receptors in domesticated animals of commercial interest
(Universidade Federal do PampaCampus Uruguaiana, 2015)
Commentary: Arginine vasopressin receptor 1a is a therapeutic target for castration-resistant prostate cancer
(Frontiers Media, 2020-01-10)
Prostate cancer patients managed with androgen-deprivation therapy usually recur after a few years and the disease gradually becomes castration-resistant prostate cancer (CRPC). The role of tumor cell plasticity, including ...
Expression of arginine vasopressin type 2 receptor in canine mammary tumours: preliminary results
(Elsevier, 2020-08)
The aims of this study were to investigate the potential association of arginine vasopressin type 2 receptor (AVPR2) in canine mammary tumours with expression of oestrogen receptors α (ORα) and β (ORβ) and clinicopathological ...
Anticancer activity of repurposed hemostatic agent desmopressin on AVPR2‑expressing human osteosarcoma
(Spandidos Publications, 2021-03-26)
Osteosarcoma is the most prevalent primary bone malignancy. Due to its high aggressiveness, novel treatment strategies are urgently required to improve survival of patients with osteosarcoma, especially those with advanced ...
Hyponatremia resulting from Arginine Vasopressin Receptor 2 gene mutation
(Springer, 2007-03)
Chronic hyponatremia, unless associated with extracellular fluid volume expansion, is an infrequent electrolyte imbalance in pediatrics. We report an infant with chronic hyponatremia suggestive of a syndrome of inappropriate ...
Preclinical efficacy of [V 4 Q 5 ]dDAVP, a second generation vasopressin analog, on metastatic spread and tumor-associated angiogenesis in colorectal cancer
(Korean Cancer Association, 2018-06)
Purpose Control of metastatic spread of colorectal cancer (CRC) remains as a major therapeutic challenge. [V 4 Q 5 ]dDAVP is a vasopressin peptide analog with previously reported anticancer activity against carcinoma tumors. ...
Development and therapeutic potential of vasopressin synthetic analog [V4Q5]dDAVP as a novel anticancer agent
(Elsevier Academic Press Inc., 2020-01)
Since its discovery, arginine vasopressin (AVP) was subjected to several modifications with the aim of obtaining novel derivatives with increased potency and selectivity for biomedical use. Desmopressin (dDAVP) is a first ...
Reduced vasopressin receptors activation mediates the anti-depressant effects of fluoxetine and venlafaxine in bulbectomy model of depression
(Springer, 2016-03)
Rationale: In response to stress, corticotropin releasing hormone (CRH) and vasopressin (AVP) are released from the hypothalamus, activate their receptors (CRHR1, CRHR2 or AVPr1b), and synergistically act to induce ...
No association between genetic variants in MAOA, OXTR, and AVPR1a and cooperative strategies
(2020-12)
The effort to understand the genetic basis of human sociality has been encouraged by the diversity and heritability of social traits like cooperation. This task has remained elusive largely because most studies of sociality ...