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Redox properties of the adenoside triphosphate-sensitive K+ channel in brain mitochondria
(WILEY-LISS, 2008)
Brain mitochondrial ATP-sensitive K+ channel (mito-K-ATP) opening by diazoxide protects against ischemic damage and excitotoxic cell death. Here we studied the redox properties of brain mito-K-ATP. Mito-K-ATP activation ...
Diazoxide protects against methylmalonate-induced neuronal toxicity
(Academic Press Inc Elsevier ScienceSan DiegoEUA, 2006)
Effects of a high fat diet on liver mitochondria: increased ATP-sensitive K(+) channel activity and reactive oxygen species generation
(SPRINGER/PLENUM PUBLISHERS, 2010)
High fat diets are extensively associated with health complications within the spectrum of the metabolic syndrome. Some of the most prevalent of these pathologies, often observed early in the development of high-fat dietary ...
Muscarinic stimulation and pinacidil produce similar facilitation of tachyarrhythmia induction in rat isolated atria
(Academic Press Ltd- Elsevier Science LtdLondonInglaterra, 2013)
Alpha-2 adrenoceptors are present in rat aorta smooth muscle cells, and their action is mediated by ATP-sensitive K+ channels
(Nature Publishing Group, 2000-10-01)
1 the role of alpha (2)-adrenoceptors in the response of aorta smooth muscle rings to the alpha (2)- adrenoceptors agonists UK 14,304 and clonidine was studied.2 Stimulation by 1-10 nM UK 14,304 caused dose-dependent ...
Redox regulation of the mitochondrial K(ATP) channel in cardioprotection
(ELSEVIER SCIENCE BV, 2011)
The mitochondrial ATP-sensitive potassium channel (mK(ATP)) is important in the protective mechanism of ischemic preconditioning (IPC). The channel is reportedly sensitive to reactive oxygen and nitrogen species, and the ...
The peripheral L-arginine-nitric oxide-cyclic GMP pathway and ATP-sensitive K+ channels are involved in the antinociceptive effect of crotalphine on neuropathic pain in rats
(LIPPINCOTT WILLIAMS & WILKINSPHILADELPHIA, 2012)
Crotalphine, a 14 amino acid peptide first isolated from the venom of the South American rattlesnake Crotalus durissus terrificus, induces a peripheral long-lasting and opioid receptor-mediated antinociceptive effect in a ...
Mitochondrial energy metabolism and redox responses to hypertriglyceridemia
(SPRINGER/PLENUM PUBLISHERS, 2011)
In this work we review recent findings that explain how mitochondrial bioenergetic functions and redox state respond to a hyperlipidemic in vivo environment and may contribute to the maintenance of a normal metabolic ...