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Blocking ATP-releasing channels prevents high extracellular ATP levels and airway hyperreactivity in an asthmatic mouse model
(AMER PHYSIOLOGICAL SOC, 2021)
Allergic asthma is a chronic airway inflammatory response to different triggers like inhaled allergens. Excessive ATP in fluids from patients with asthma is considered an inflammatory signal and an important autocrine/paracrine ...
Homeostasis de ATP extracelular en eritrocitos: interregulación y consecuencias funcionales
(Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica, 2015)
Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration
(Elsevier, 2016)
Our previous reports indicate that ligand-induced alpha(v)beta(3) integrin and Syndecan-4 engagement increases focal adhesion formation and migration of astrocytes. Additionally, ligated integrins trigger ATP release through ...
Kinetics of extracellular ATP in mastoparan 7-activated human erythrocytes
(Elsevier, 2013-10)
Background: The peptide mastoparan 7 (MST7) stimulated ATP release in human erythrocytes. We explored intraand extracellular processes governing the time-dependent accumulation of extracellular ATP (i.e., ATPe kinetics). ...
Extracellular ATP hydrolysis in Caco-2 human intestinal cell line
(Elsevier Science, 2021-10)
Extracellular nucleotides and nucleosides activate signaling pathways that play major roles in the physiology and pathophysiology of the gastrointestinal tract. Ectonucleotidases hydrolyze extracellular nucleotides and ...
Peripheral mechanisms underlying the essential role of P2X7 receptors in the development of inflammatory hyperalgesia
(Elsevier Science BvAmsterdamHolanda, 2010)
Human erythrocytes release ATP by a novel pathway involving VDAC oligomerization independent of pannexin-1
(Springer Nature, 2018-12)
We previously demonstrated that the translocase protein TSPO2 together with the voltage-dependentanion channel (VDAC) and adenine nucleotide transporter (ANT) were involved in a membrane transportcomplex in human red blood ...