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The atorvastatin metabolic phenotype shift is influenced by interaction of drug-transporter polymorphisms in Mexican population: results of a randomized trial
(Nature Research, 2020-06-01)
Atorvastatin (ATV) is a blood cholesterol-lowering drug used to prevent cardiovascular events, the leading cause of death worldwide. As pharmacokinetics, metabolism and response vary among individuals, we wanted to determine ...
Atorvastatin increases the expression of long non-coding rnas arsr and chrome in hypercholesterolemic patients: A pilot study
(MDPI, 2020)
Atorvastatin is extensively used to treat hypercholesterolemia. However, the wide interindividual variability observed in response to this drug still needs further elucidation. Nowadays, the biology of long non-coding RNAs ...
Influence of SCARB1 polymorphisms on serum lipids of hypercholesterolemic individuals treated with atorvastatin
(ELSEVIER SCIENCE BV, 2010)
Background: The SR-BI is a key component on the cholesterol metabolism. Polymorphisms in the SR-BI gene (SCARB1) were related with variations on plasma lipoprotein profile and other risk factors for cardiovascular disease. ...
Hip circumference is associated with high density lipoprotein cholesterol response following statin therapy in hypertensive subjects
(Editrice Kurtis S R LMilanItália, 2011)
Atorvastatin Improves Ventricular Remodeling After Myocardial Infarction By Interfering With Collagen Metabolism
(Public Library ScienceSan Francisco, 2016)
Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin
(2011-11-10)
Abstract
Background
Apolipoprotein E (apoE) is a key component of the lipid metabolism. Polymorphisms at the apoE gene (APOE) have been associated with cardiovascular ...
Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin
(2011-11-10)
Abstract
Background
Apolipoprotein E (apoE) is a key component of the lipid metabolism. Polymorphisms at the apoE gene (APOE) have been associated with cardiovascular disease, ...
Anti-inflammatory effect of atorvastatin ameliorates insulin resistance in monosodium glutamate-treated obese mice
(W B SAUNDERS CO-ELSEVIER INC, 2010)
Considering that inflammation contributes to obesity-induced insulin resistance and that statins have been reported to have other effects beyond cholesterol lowering, the present study aimed to it whether atorvastatin ...
MicroRNA-33b is a potential non-invasive biomarker for response to atorvastatin treatment in chilean subjects with hypercholesterolemia: a pilot study
(Frontiers Media, 2021)
Evidence accumulated so far indicates that circulating levels of microRNAs (miRNAs) are associated with several pathologies. Therefore, differential expression of extracellular miRNAs exhibits promising potential for ...