Neuropathic and inflammatory pain results from cellular and molecular changes in dorsal root ganglion (DRG) neurons. The type-2 receptor for Angiotensin-II (AT2R) has been involved in this type of pain. However, the ...

Introducción: The existence of a “Deuteronomistic History,” consisting of the books of Deuteronomy, Joshua, Judges, Samuel, and Kings, is under review.1 Is this scholarly construct an accurate understanding of what ancient ...

Although most of effects of Angiotensin II (Ang II) related to cardiac remodelling can be attributed to type 1 Ang II receptor (AT(1)R), the type 2 receptor (AT(2)R) has been shown to be involved in the development of some ...

The angiotensin II type 1 receptor (AT1R) is involved in the development of cardiac hypertrophy promoted by thyroid hormone. Recently, we demonstrated that triiodothyronine (T-3) rapidly increases AT1R mRNA and protein ...

A high-fat diet (HFD) induces an increase in arterial pressure and a decrease in baroreflex function, which may be associated with increased expression of angiotensin type 1 receptor (AT1R) and pro-inflammatory cytokine ...

A angiotensina II (AngII) e um potente agente do sistema renina-angiotensina participando da regulacao da pressao arterial e na homeostase hidromineral. Seu efeitos fisiologicos sao mediados pelos receptores tipo 1 (AT1) ...

tAT2 receptor (AT2R) plays a functional role in foetal development. Its expression declines in most tissuessoon after birth but stays high in sensory areas of the adult nervous system. In the dorsal root ganglia (DRG)the ...

Central angiotensin II through AT1 receptors (AT1-R), closely interact with sympathetic nervous system (SNS) in the maintenance of renal sodium equilibrium under normal and pathological conditions. Our aim was to unmask ...

In animal models, interstitial angiotensin II (ang II) and AT1 receptor (AT1R) are key mediators of renal inflammation and fibrosis in progressive chronic nephropathies. We hypothesized that these molecules were overexpressed ...