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Divergent regulatory mechanisms in the response of respiratory chain component genes to carbohydrates suggests a model for gene evolution after duplication
(Landes Bioscience, 2009-04)
The biogenesis of the plant mitochondrial respiratory chain needs the coordinated synthesis and assembly of the products of more than 100 genes located in the nucleus and within the organelle. One of the factors that ...
Polymorphisms in the AR and PSA Genes as Markers of Susceptibility and Aggressiveness in Prostate Cancer
(Taylor & Francis Inc, 2010-11-01)
The study of genes involved in androgen pathway can contribute to a better knowledge of prostate cancer. Our aim was to examine if polymorphisms in prostate-specific antigen (PSA) and androgen receptor (AR) genes were ...
Polymorphisms in the AR and PSA Genes as Markers of Susceptibility and Aggressiveness in Prostate Cancer
(Taylor & Francis Inc, 2010-11-01)
The study of genes involved in androgen pathway can contribute to a better knowledge of prostate cancer. Our aim was to examine if polymorphisms in prostate-specific antigen (PSA) and androgen receptor (AR) genes were ...
Coarse-grain reconstruction of genetic networks from expression levels
(Elsevier Science, 2011-06)
In the postgenome era many efforts have been dedicated to systematically elucidate the complex web of interacting genes and proteins. These efforts include experimental and computational methods. Microarray technology ...
Plant growth-promoting genes can switch to be virulence factors via horizontal gene transfer
(Springer, 2018-10)
There are increasing evidences that horizontal gene transfer (HGT) is a critical mechanism of bacterial evolution, while its complete impact remains unclear. A main constraint of HGT effects on microbial evolution seems ...
Mining Gene Regulatory Networks by Neural Modeling of Expression Time-Series
(IEEE Computer Society, 2015-11)
Discovering gene regulatory networks from data is one of the most studied topics in recent years. Neural networks can be successfully used to infer an underlying gene network by modeling expression profiles as times series. ...
Cytokine-enhanced vaccine and suicide gene therapy as adjuvant treatments of metastatic melanoma in a horse
(British Veterinary Association, 2009-02)
We evaluated the safety, efficacy and anti-tumour effects of a surgery adjuvant treatment on an equine patient with metastatic malignant melanoma. This approach combined suicide gene therapy with a subcutaneous vaccine ...
Gene filtering with optimal threshold selection
(Universidad Autónoma de Barcelona, 2012)
Gene filtering is a useful preprocessing technique often applied to microarray datasets. However, it is no common practice because clear guidelines are lacking and it bears the risk of excluding some potentially relevant ...