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Antidepressant imipramine diminishes stress-induced inflammation in the periphery and central nervous system and related anxiety- and depressive- like behaviors
(2016)
In order to relieve anxiety and depression accompanying stress, physicians resort to tricyclic antidepressants, such as imipramine. We had previously shown that imipramine reversed stress-induced social avoidance behavior, ...
Grooming analysis algorithm: Use in the relationship between sleep deprivation and anxiety-like behavior
(Elsevier B.V., 2013-03-05)
Increased anxiety is a classic effect of sleep deprivation. However, results regarding sleep deprivation-induced anxiety-like behavior are contradictory in rodent models. the grooming analysis algorithm is a method developed ...
Maternal testosterone exposure increases anxiety-like behavior and impacts the limbic system in the offspring
(National Academic Sciences, 2015)
During pregnancy, women with polycystic ovary syndrome (PCOS) display high circulating androgen levels that may affect the fetus and increase the risk of mood disorders in offspring. This study investigated whether maternal ...
Stress during development alters anxiety-like behavior and hippocampal neurotransmission in male and female rats
(Elsevier B.V., 2012-01-01)
Epidemiological data indicate that early stress increases vulnerability to psychiatric disorders, including anxiety and depression. in the present study we sought to investigate the long-term behavioral and neurochemical ...
Alterations in opioid inhibition cause widespread nociception but do not affect anxiety-like behavior in oral cancer mice
(2017-11-05)
Widespread pain and anxiety are commonly reported in cancer patients. We hypothesize that cancer is accompanied by attenuation of endogenous opioid-mediated inhibition, which subsequently causes widespread pain and anxiety. ...
Tonic modulation of anxiety-like behavior by corticotropin-releasing factor (CRF) type 1 receptor (CRF1) within the medial prefrontal cortex (mPFC) in male mice: Role of protein kinase A (PKA)
(Elsevier B.V., 2014-07-01)
The medial prefrontal cortex (mPFC) and the neuropeptide corticotropin-releasing factor (CRF) have recently been receiving more attention from those interested in the neurobiology of anxiety. Here, we investigated the CRF ...
Early protein malnutrition negatively impacts physical growth and neurological reflexes and evokes anxiety and depressive-like behaviors
(Elsevier Inc, 2014-03)
Malnutrition is a worldwide problem affecting millions of unborn and young children during the most vulnerable stages of their development. In humans, poor maternal nutrition is a major cause of intrauterine growth restriction ...
Effects of cocaine base paste on anxiety-like behavior and immediate-early gene expression in nucleus accumbens and medial prefrontal cortex of female mice
(Springer, 2019-07)
RATIONALE:Cocaine base paste (CBP) is an illegal drug of abuse usually consumed by adolescents in a socio-economically vulnerable situation. Repeated drug use targets key brain circuits disrupting the processes that underlie ...
Dengue-3 encephalitis promotes anxiety-like behavior in mice
(Elsevier/North-Holland Biomedical Press, 2015)
Transient serotonin depletion at adolescence, but not at early infancy, reduced subsequent anxiety-like behavior and alcohol intake in female mice
(Springer, 2021-01)
Serotonin (5-HT) plays an important role in the organization of the central nervous system and in the development of social interaction deficits and psychiatric disorders, including anxiety, depression, and addiction ...