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Tetranucleotide ggga motif primary transcripts: novel target site for antisense design
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 1998)
Selecting effective antisense target sites on a given mRNA molecule constitutes a major problem in antisense therapeutics. By trial-and-error, only 1 in 18 (6%) of antisense oligonucleotides designed to target the primary ...
Progress in the use of antisense oligonucleotides for vaccine improvement
(2020-02-01)
Antisense oligonucleotides (ASOs) are synthetically prepared short single-stranded deoxynucleotide sequences that have been validated as therapeutic agents and as a valuable tool in molecular driving biology. ASOs can block ...
Neighboring gene regulation by antisense long Non-Coding RNAs
(2015)
Antisense transcription, considered until recently as transcriptional noise, is a very common phenomenon in human and eukaryotic transcriptomes, operating in two ways based on whether the antisense RNA acts in cis or in ...
Tetranucleotide GGGA motif in primary RNA transcripts: Novel target site for antisense design
(1998)
Selecting effective antisense target sites on a given mRNA molecule constitutes a major problem in antisense therapeutics. By trial-and-error, only 1 in 18 (6%) of antisense oligonucleotides designed to target the primary ...
Identification of sense and antisense transcripts regulated by drought in sugarcane
(SPRINGERDORDRECHT, 2012-07)
Sugarcane is an important sugar and energy crop that can be used efficiently for biofuels production. The development of sugarcane cultivars tolerant to drought could allow for the expansion of plantations to sub-prime ...
Tetranucleotide ggga motif primary transcripts: novel target site for antisense designTHE JOURNAL OF BIOLOGICAL CHEMISTRY (IMPRESA)J. Biol. Chem.
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2017)
Targeting kupffer cells with antisense oligonucleotides
(Frontiers in Bioscience, 2002)
© 2002 Frontiers in Bioscience. All rights reserved.During proinflammatory reactions such as endotoxemia, ischemia-reperfusion and immune reactions, excessive amounts of cytokines and prostanoids are released resulting in ...
Non-coding transcript in T cells (NTT): Antisense transcript activates PKR and NF-kappa B in human lymphocytes
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
T cell activation is a complex process involving many steps and the role played by the non-protein-coding RNAs (ncRNAs) in this phenomenon is still unclear. The non-coding T cells transcript (NTT) is differentially expressed ...
Hormone-dependent expression of a steroidogenic acute regulatory protein natural antisense transcript in MA-10 mouse tumor Leydig cells
(Public Library of Science, 2011-08)
Cholesterol transport is essential for many physiological processes, including steroidogenesis. In steroidogenic cells hormone-induced cholesterol transport is controlled by a protein complex that includes steroidogenic ...