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História do surgimento e desenvolvimento das drogas antiepilépticasHistorical origin and antiepileptic drug development
(Liga Brasileira de Epilepsia (LBE), 2006)
Antiepileptic drug therapy and recommendations for withdrawal in patients with seizures and epilepsy due to neurocysticercosis
(Taylor and Francis, 2016)
INTRODUCTION: Neurocysticercosis (NCC) is a leading causes of secondary epilepsy worldwide. There is increasing evidence on the epileptogenic role of NCC, and the presence of edema, calcified scars, gliosis and hippocampal ...
CHALCONSEMICARBAZONE: A NEW SCAFFOLD FOR ANTIEPILEPTIC DRUG DISCOVERY
(Sociedad Chilena de Química, 2010)
The importance of drug repurposing in the field of antiepileptic drug development
(Springer, 2016)
Drug repurposing involves finding new therapeutic uses for existing drugs, including marketed, discontinued, shelved, and investigational drugs. The advantages of this strategy are many: reduced drug development timeline, ...
Antiepileptic Drugs in Treatment of Pain Caused by Diabetic Neuropathy
Pain is frequent in diabetic neuropathy and is very hard to manage. Antiepileptic drugs have been used in treating pain for several decades. Their effectiveness has been described in different types of neuropathic pain, ...
Aromatic antiepileptic drugs and mitochondrial toxicity: Effects on mitochondria isolated from rat liver
(Pergamon-Elsevier B.V. Ltd, 2008-08-01)
Idiosyncratic hepatotoxicity is a well-known complication associated with aromatic antiepileptic drugs (AAED), and it has been suggested to occur due to the accumulation of toxic arene oxide metabolites. Although there is ...
Aromatic antiepileptic drugs and mitochondrial toxicity: Effects on mitochondria isolated from rat liver
(Pergamon-Elsevier B.V. Ltd, 2008-08-01)
Idiosyncratic hepatotoxicity is a well-known complication associated with aromatic antiepileptic drugs (AAED), and it has been suggested to occur due to the accumulation of toxic arene oxide metabolites. Although there is ...
Antiepileptic drugs: a study of 1028 cases registered by the Sao Paulo intoxication Control Center
(W B Saunders Co LtdLondonInglaterra, 2005)
Higher evening antiepileptic drug dose for nocturnal and early-morning seizures
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2011)
We describe 17 children with nocturnal or early-morning seizures who were switched to a proportionally higher evening dose of antiepileptic drugs and were retrospectively reviewed for seizure outcome and side effects. Of ...