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Neonatal inhibition of DNA methylation disrupts testosterone-dependent masculinization of neurochemical phenotype
(Endocrine Society, 2020-01)
Many neural sex differences are differences in the number of neurons of a particular phenotype. For example, male rodents have more calbindin-expressing neurons in the medial preoptic area (mPOA) and bed nucleus of the ...
Sensibilidade diferenciada dos núcleos anteroventral periventricular e arqueado ao estradiol como parte dos mecanismos de retroalimentação positiva e negativa sobre o eixo gonadal
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Ciências Biológicas - Fisiologia e FarmacologiaUFMG, 2017-12-01)
The preovulatory surge of luteinizing hormone (LH) is a key event responsible for ovulation and fertility in females. LH secretion is under estradiol (E2) control, through negative and positive feedback mechanisms that ...
Alpha-oestrogen and progestin receptor expression in the hypothalamus and preoptic area dopaminergic neurones during oestrous in cycling rats
(BLACKWELL PUBLISHING, 2008)
A secretory surge of prolactin occurs on the afternoon of oestrous in cycling rats. Although prolactin is regulated by ovarian steroids, plasma oestradiol and progesterone levels do not vary during oestrous. Because prolactin ...
EXPRESSION OF COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT IN THE RAT FOREBRAIN DURING POSTNATAL DEVELOPMENT
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Cocaine- and amphetamine-regulated transcript (CART) is widespread in the rodent brain. CART has been implicated in many different functions including reward, feeding, stress responses, sensory processing, learning and ...
GABAB receptor antagonism from birth to weaning permanently modifies Kiss1 expression in hypothalamus and gonads in mice
(Karger, 2021-12)
The kisspeptin gene Kiss1 is expressed in two hypothalamic areas: anteroventral periventricular nucleus/periventricular nucleus (AVPV/PeN) and arcuate nucleus (ARC), and also in gonads. Several pieces of evidence suggests ...
Chemical identity and connections of medial preoptic area neurons expressing melanin-concentrating hormone during lactation
(ELSEVIER SCIENCE BV, 2010)
Lactation is an energy-demanding process characterized by massive food and water consumption, cessation of the reproductive cycle and induction of maternal behavior. During lactation, melanin-concentrating hormone (MCH) ...
The Ventral Premammillary Nucleus Links Fasting-Induced Changes in Leptin Levels and Coordinated Luteinizing Hormone Secretion
(SOC NEUROSCIENCE, 2009)
Physiological conditions of low leptin levels like those observed during negative energy balance are usually characterized by the suppression of luteinizing hormone (LH) secretion and fertility. Leptin administration ...
Ampk Alpha 2 In Kiss1 Neurons Is Required For Reproductive Adaptations To Acute Metabolic Challenges In Adult Female Mice
(Endocrine SocWashington, 2016)
CHARACTERIZATION OF Kiss1 NEURONS USING TRANSGENIC MOUSE MODELS
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Humans and mice with loss-of-function mutations of the genes encoding kisspeptins (Kiss1) or kisspeptin receptor (Kiss1r) are infertile due to hypogonadotropic hypogonadism. Within the hypothalamus, Kiss1 mRNA is expressed ...
Cardiovascular responses to microinjection of L-glutamate into the NTS in AV3V-lesioned rats
(Elsevier B.V., 2004-10-29)
The excitatory amino acid L-glutamate injected into the nucleus of the solitary tract (NTS) in unanesthetized rats similar to peripheral chemoreceptor activation increases mean arterial pressure (MAP) and reduces heart ...