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Design and synthesis of angucyclinone ab-pyrido[2,3-d] pyrimidine analogues
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Studies on quinones. Part 44: novel angucyclinone n-heterocyclic analogues endowed with antitumoral activity
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
Design and synthesis of angucyclinone 5-aza analogues
(THIEME, 2006)
Studies on quinones. Part 44: Novel angucyclinone N-heterocyclic analogues endowed with antitumoral activity
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
In the search for new potentially anticancer drugs, series of angucyclinone aza-analogues containing pyridine and pyridopyridazine rings have been designed and synthesized by a highly efficient sequence involving a one-pot ...
Design and synthesis of angucyclinone AB-pyrido[2,3-d] pyrimidine analogues
(PERGAMON-ELSEVIER SCIENCE LTD, 2008)
The preparation of two pyrimido[4,5-c]isoquinoline-7, 10-quinones from acylhydroquinones and 1,3-dimethyl-5-aminouracil and their cycloadditions with 1-trimethylsilyloxybutadiene and 1-dimethylamino-3-methyl-1-azabutadiene ...
Design and synthesis of angucyclinone 5-aza analogues
(GEORG THIEME VERLAG KG, 2006)
A highly efficient one-pot procedure for the synthesis of phenanthridine-1,7,10-triones from acylbenzoquinones and cyclic enaminones is reported. The cycloaddition reactions of these quinones with 1-trimethylsilyloxybutadiene ...
The solar-chemical photo-Friedel-Crafts heteroacylation of 1,4-quinones
(PERGAMON-ELSEVIER SCIENCE LTD, 2011)
Photochemical reactions between 1,4-benzo- and 1,4-naphthoquinone and several heteroaromatic carbaldehydes were investigated under solar irradiation conditions. These reactions gave the corresponding heteroacylated ...
Inhibition of human topoisomerase I and activation of caspase-3 by aza-angucyclinones and arylaminopyrimido[4,5-c]isoquinoline-7,10-quinones
(SPANDIDOS PUBL LTD, 2012)
Cancer is the second cause of death in the world after cardiovascular diseases. Cancer cells acquire capacities not present in normal cells, such as self-sufficiency, resistance to antiproliferative stimuli, evasion of ...