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Micro and nanosystems for delivering local anesthetics
(Informa Healthcare, 2012-12-01)
Introduction: One of the most common strategies for pain control during and after surgical procedures is the use of local anesthetics. Prolonged analgesia can be safely achieved with drug delivery systems suitably chosen ...
Micro and nanosystems for delivering local anesthetics
(Informa Healthcare, 2012-12-01)
Introduction: One of the most common strategies for pain control during and after surgical procedures is the use of local anesthetics. Prolonged analgesia can be safely achieved with drug delivery systems suitably chosen ...
Local anesthetics inhibit Ca-ATPase in masticatory muscles
(SAGE Publications, 2010-04)
Local anesthetics have myotoxic effects and inhibit Ca-ATPase activity and Ca transport in skeletal muscles. Such effects have not been fully elucidated in masticatory muscles. We tested the hypothesis that local anesthetics ...
Drug delivery systems for local anesthetics
(2010-06-25)
Although technological innovations in the area of drug delivery claim for varied benefits, increasing the drug therapeutic index for human clinical application is the main goal pursued. Drug delivery systems for local ...
Benzocaine-loaded polymeric nanocapsules: Study of the anesthetic activities
(Wiley-Blackwell, 2012-03-01)
This paper describes a comparison of different polymeric nanocapsules (NCs) prepared with the polymers poly(d,l-lactide-co-glycolide), poly(l-lactide) (PLA), and poly(e-caprolactone) and used as carrier systems for the ...
Benzocaine-loaded polymeric nanocapsules: Study of the anesthetic activities
(Wiley-Blackwell, 2012-03-01)
This paper describes a comparison of different polymeric nanocapsules (NCs) prepared with the polymers poly(d,l-lactide-co-glycolide), poly(l-lactide) (PLA), and poly(e-caprolactone) and used as carrier systems for the ...
Preferential location of lidocaine and etidocaine in lecithin bilayers as determined by EPR, fluorescence and H-2 NMR
(Elsevier Science BvAmsterdamHolanda, 2008)
Physicochemical Stability of Poly(lactide-co-glycolide) Nanocapsules Containing the Local Anesthetic Bupivacaine
(Soc Brasileira Quimica, 2010-01-01)
This paper describes the preparation of poly(DL-lactide-co-glicolide) (PLGA) nanocapsules as a drug carrier system for the local anesthetic bupivacaine. The system was characterized and its stability investigated. The ...
Physicochemical Stability of Poly(lactide-co-glycolide) Nanocapsules Containing the Local Anesthetic Bupivacaine
(Soc Brasileira Quimica, 2010-01-01)
This paper describes the preparation of poly(DL-lactide-co-glicolide) (PLGA) nanocapsules as a drug carrier system for the local anesthetic bupivacaine. The system was characterized and its stability investigated. The ...