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New atropisomers derived from amidinoquinoxaline N-oxides: Synthesis and NMR characterization
(Elsevier Science, 2010-10)
The complete 1H and 13C NMR characterization of some representative examples of five and six-membered amidinoquinoxaline N-oxides 1 with dissymmetric aryl substituents and their methiodides 2 is reported. Compounds 1 were ...
Amidinoquinoxaline-Based Nitrones as Lipophilic Antioxidants
(MDPI, 2021-08)
The potential of nitrones (N-oxides) as therapeutic antioxidants is due to their ability to counteract oxidative stress, mainly attributed to their action as radical scavengers toward C- and O-centered radicals. Among them, ...
Amidinoquinoxaline N-oxides: spin trapping of O- and C-centered radicals
(Royal Society of Chemistry, 2017-09)
Amidinoquinoxaline N-oxides represent a novel family of heterocyclic spin traps. In this work, their ability to trap O- and C-centered radicals was tested using selected derivatives with different structural modifications. ...
Atropisomerism in amidinoquinoxaline N-oxides: effect of the ring size and substituents on the enantiomerization barriers
(American Chemical Society, 2015-01)
The atropisomerism of novel 2,3-dihydro1H-pyrimido[1,2-a]quinoxaline 6-oxides 1 bearing dissymmetric (ortho-substituted) 5-aryl residues and the homologous 1,2-dihydroimidazo[1,2-a]quinoxaline 5-oxides 2 was investigated. ...