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Biomarkers for dementia in Latin American countries: Gaps and opportunities
(Wiley, 2022)
Limited knowledge on dementia biomarkers in Latin American and Caribbean (LAC) countries remains a serious barrier. Here, we reported a survey to explore the ongoing work, needs, interests, potential barriers, and opportunities ...
Systemic lupus erythematosus: The search for the ideal biomarker
(SAGE Publications, 2020)
During the last decades, there has been an increased interest in the discovery and validation of biomarkers that reliably reflect specific aspects of lupus. Although many biomarkers have been developed, few of them have ...
Mild cognitive impairment (part 2): Biological markers for diagnosis and prediction of dementia in Alzheimer's disease
(2013-10-14)
To present a critical review of publications reporting on the rationale and clinical implications of the use of biomarkers for the early diagnosis of Alzheimer's disease (AD). Methods: We conducted a systematic search of ...
Mild cognitive impairment (part 2): Biological markers for diagnosis and prediction of dementia in Alzheimer's disease
(2013-10-14)
To present a critical review of publications reporting on the rationale and clinical implications of the use of biomarkers for the early diagnosis of Alzheimer's disease (AD). Methods: We conducted a systematic search of ...
Systematic review: microRNAs as potential biomarkers in mild cognitive impairment diagnosis
(Frontiers Media, 2022)
The rate of progression from Mild Cognitive Impairment (MCI) to Alzheimer's disease (AD) is estimated at > 10% per year, reaching up to 80-90% after 6 years. MCI is considered an indicator of early-stage AD. In this context, ...
Biomarkers for susceptibility to infection and disease severity in human malaria
(2011)
Malaria remains a major infectious disease that affects millions of people. Once infected with Plasmodium parasites, a host can develop a broad range of clinical presentations, which result from complex interactions between ...
Cerebrospinal fluid and blood biomarkers for neurodegenerative dementias: An update of the Consensus of the Task Force on Biological Markers in Psychiatry of the World Federation of Societies of Biological Psychiatry
(Taylor and Francis, 2018)
In the 12 years since the publication of the first Consensus Paper of the WFSBP on biomarkers of neurodegenerative dementias, enormous advancement has taken place in the field, and the Task Force takes now the opportunity ...
Emerging Noninvasive Biomarkers for Early Detection of Alzheimer's Disease
(2012)
Alzheimer's disease (AD) diagnosis still depends on the triad of clinical, imaging and neuropsychological testing. The development of accurate, easy to use and inexpensive biological markers for AD is a long-standing ...
Plasma Tau Variants Detected by a Novel Anti-Tau Monoclonal Antibody: A Potential Biomarker for Alzheimer’s Disease
(IOP Publishing, 2020)
Background: A major drawback in Alzheimer's disease (AD) is the lack of validated biomarkers for routine clinical diagnostic. We have reported earlier a novel blood biomarker, named Alz-tau (R), based on variants of platelet ...