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Structure of the Human ACP-ISD11 Heterodimer
(American Chemical Society, 2019-10)
In recent years, the mammalian mitochondrial protein complex for iron-sulfur cluster assembly has been the focus of important studies. This is partly because of its high degree of relevance in cell metabolism and because ...
Rescuing the Rescuer: On the Protein Complex between the Human Mitochondrial Acyl Carrier Protein and ISD11
(American Chemical Society, 2018-06)
Iron-sulfur clusters are essential cofactors in many biochemical processes. ISD11, one of the subunits of the protein complex that carries out the cluster assembly in mitochondria, is necessary for cysteine desulfurase ...
Novel topical skin hydration agent containing Anadenanthera colubrina polysaccharide-standardized herbal preparation
(2020-07-01)
Background: Hydration is an important factor to promote skin barrier function, metabolism, and appearance. In this process, the presence of aquaglyceroporins, envelope and lipid synthesis, and metabolism proteins are ...
Bone resorptive activity in symptomatic and asymptomatic apical lesions of endodontic origin
(Springer Verlag, 2017)
G120K-PEG, a human GH antagonist, decreases GH signal transduction in the liver of mice
(Elsevier Ireland LtdClareIrlanda, 2002)
Activation of the low molecular weight protein tyrosine phosphatase in keratinocytes exposed to hyperosmotic stress
(Public Library Science, 2015-03-17)
Herein, we provide new contribution to the mechanisms involved in keratinocytes response to hyperosmotic shock showing, for the first time, the participation of Low Molecular Weight Protein Tyrosine Phosphatase (LMWPTP) ...
Efeito da temperatura na enzima 2-trans-enoil-ACP (CoA) redutase (EC 1.3.1.9) de Mycobacterium tuberculosis em complexo com o NADH: um estudo por simulação pela dinâmica molecular
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2009)
Temperature can interfere with protein structure and function, affecting its ability to bind to other molecules, its conformational microstates distribution, as well as the rate of its enzymatic reactions. Since the mid-20th ...
Efeito da temperatura na enzima 2-trans-enoil-ACP (CoA) redutase (EC 1.3.1.9) de Mycobacterium tuberculosis em complexo com o NADH: um estudo por simulação pela dinâmica molecular
(Pontifícia Universidade Católica do Rio Grande do SulPorto Alegre, 2009)
Temperature can interfere with protein structure and function, affecting its ability to bind to other molecules, its conformational microstates distribution, as well as the rate of its enzymatic reactions. Since the mid-20th ...
Complexos de rênio(I) e cobalto(III) como candidatos a metalofármacos antitumorais
(Universidade Federal de Minas GeraisUFMG, 2017-03-27)
The present study involved the investigation of rhenium(I) and cobalt(M) complexes coitaining Schiff bases with antiproliferative activity for the development of new antitumor metallopharmaceuticals candidates. Rhenium(I) ...
Cysteine proteinase inhibitors regulate human and mouse osteoclastogenesis by interfering with RANK signaling
(2013-07-01)
The cysteine proteinase inhibitor cystatin C inhibited RANKL-stimulated osteoclast formation in mouse bone marrow macrophage cultures, an effect associated with decreased mRNA expression of Acp5, Calcr, Ctsk, Mmp9, Itgb3, ...