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ACELLULAR AND "LOW" PERTUSSIS VACCINES: ADVERSE EVENTS AND THE ROLE OF MUTATIONS
(Inst Medicina Tropical Sao PauloSao PauloBrasil, 2009)
Immunogenicity of a combined DTPa-HB vaccine co-administered with Haemophilus influenzae type B conjugate vaccine (PRP-T) for primary and booster vaccinations
(Brazilian Society of Infectious Diseases, 2005-10-01)
OBJECTIVE: To evaluate the immunogenicity of a combined DTPa-HB vaccine co-administered with Haemophilus influenzae type b conjugate vaccine (PRP-T) in Brazilian infants. MATERIAL AND METHODS: A prospective and open clinical ...
Outer membrane vesicles derived from Bordetella parapertussis as an acellular vaccine against Bordetella parapertussis and Bordetella pertussis infection
(Elsevier, 2013-10)
Bordetella parapertussis, a close related species of B. pertussis, can also cause the disease named pertussis or whooping cough. The number of cases caused by this related pathogen has risen sustained in the last years. ...
New Pertussis Vaccines: A Need and a Challenge
(Springer Verlag Berlín, 2019-11)
Effective diphtheria, tetanus toxoids, whole-cell pertussis (wP) vaccines were used for massive immunization in the 1950s. The broad use of these vaccines significantly reduced the morbidity and mortality associated with ...
Rare detection of bordetella pertussis pertactin-deficient strains in Argentina
(Centers Disease Control, 2019-11)
Pertussis resurgence had been attributed to waning vaccine immunity and Bordetella pertussis adaptation to escape vaccine-induced immunity. Circulating bacteria differ genotypically from strains used in production of ...
Acellular and "low" pertussis vaccines: adverse events and the role of mutations
(São Paulo, 2014-03-07)
Objective: to discuss the current PAHO recommendation that does not support the substitution of traditional cellular DTP vaccine by acellular DTP, and the role of mutations, in humans, as the main cause of rare adverse ...
Parent reported outcomes to measure satisfaction, acceptability, and daily life impact after vaccination with whole-cell and acellular pertussis vaccine in Chile
(Elsevier, 2020)
Aim: To compare parental satisfaction and impact on daily life among parents of children receiving whole-cell pentavalent + oral polio vaccine (Arm 1) with an acellular hexavalent vaccine (Hexaxim; Arm 2). Methods: ...