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Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
Study of the interactions established between the viral glycoproteins and their host
receptors is of critical importance for a better understanding of virus entry into cells. The
novel coronavirus SARS-CoV-2 entry into ...
ACE gene polymorphism and severe lung injury in patients with COVID-19
COVID-19 has markedly varied clinical presentations, with the majority of patients being
asymptomatic or having mild symptoms. However, severe acute respiratory disease
caused by SARS-CoV-2 is common and associated with ...
Detección rápida del coronavirus SARS-COV-2 utilizando como target el receptor ACE2, inmovilizado con una cola de cisteína en un electrodo de oro, usando técnicas de espectroscopía de impedancia
(Universidad Ricardo PalmaPE, 2020)
Resumen del Proyecto: Detección rápida del coronavirus SARS-COV-2 utilizando como target el receptor ACE2, inmovilizado con una cola de cisteína en un electrodo de oro, usando técnicas de espectroscopía de impedancia
New mass spectrometric assay for angiotensin-converting enzyme 2 activity
(Lippincott Williams & WilkinsPhiladelphiaEUA, 2006)
ACE2, the Receptor that Enables the Infection by SARS‐CoV‐2: Biochemistry, Structure, Allostery and Evaluation of the Potential Development of ACE2 Modulators
(Wiley VCH Verlag, 2020-07)
Angiotensin Converting Enzyme 2 (ACE2) is the human receptor that interacts with the Spike protein of coronaviruses, including the one that produced the 2020 coronavirus pandemic (COVID-19). Thus, ACE2 is a potential target ...
Avaliação de sistemas vasoativos: papel dos autoanticorpos na preeclâmpsia
(Universidade Federal de Minas GeraisUFMG, 2010-10-08)
Preeclampsia (PE) is a leading cause of maternal death and a major contributor to maternal and perinatal morbitidy. However, the mechanisms implicated in this disease are still poorly understood. Recent studies have shown ...
High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa
It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a crucial role in the entry of virus into the cell
to cause the final infection. To investigate the potential route of 2019-nCov infection ...
ACE2-angiotensin-(1-7)-Mas axis in renal ischaemia/reperfusion injury in rats
(Portland Press Ltd, 2010-11-01)
AngII (angiotensin II), ACE (angiotensin I-converting enzyme) and the AT(1) receptor (AngII type I receptor) are associated with the inflammatory process and microvascular dysfunction of AKI (acute kidney injury) induced ...
Interações cruzadas entre os receptores de cininas e da angiotensina II e enzima conversora da angiotensina I em músculo liso vascular e não vascular pelo rompimento seletivo dos genes que codificam os receptores de cininas
(Universidade Federal de São Paulo (UNIFESP), 2009-01-28)
Purpose: Our aim was to evaluate possible crossed interactions between kallikrein-kinin and renin-angiotensin systems in abdominal aorta and fundus stomach isolated from mice deficient in kinin B1, B2 or both sub-types B1 ...