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Dynamics of the ACE2–SARS‐CoV‐2/ SARS‐CoV spike protein interface reveal unique mechanisms
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a major public health concern.A handful of static structures now
provide molecular insights ...
Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China,
at the end of 2019, and there are currently no specific antiviral treatments or vaccines
available. SARS-CoV-2 has been shown to use ...
Neutralization of SARS-CoV-2 spike pseudotyped virus by recombinant ACE2-Ig
(Springer Nature, 2020)
From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development
The global pandemic of COVID-19 caused by SARS-CoV-2 (also known as 2019-nCoV and HCoV-19) has
posed serious threats to public health and economic stability worldwide, thus calling for development of
vaccines against ...
Selection of aptamers which binds human ACE-2 (angiotensin converting enzyme) for blocking RBD (receptor-binding domain) of SARS-CoV-2 protein S
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2022)
SARS-CoV-2 and the cardiovascular system
The coronavirus disease COVID-19 is a public health emergency caused by a novel coronavirus
named severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 infection
uses the angiotensin-converting enzyme ...
Structural basis of receptor recognition by SARS-CoV-2
A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2)
recently emerged and is rapidly spreading in humans, causing COVID-191,2
. A key to
tackling this pandemic is to understand the receptor ...
Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
Study of the interactions established between the viral glycoproteins and their host
receptors is of critical importance for a better understanding of virus entry into cells. The
novel coronavirus SARS-CoV-2 entry into ...