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Prevalência de vírus adeno-associado (AAV) e de coinfecção com papilomavírus humano (HPV) em espécime cervical de mulheres soropositivas e soronegativas para HIV
(Universidade Federal do Espírito SantoBRMestrado em Doenças InfecciosasPrograma de Pós-Graduação em Doenças InfecciosasUFES, 2009-02-12)
AAV is a parvovirus which depends of a helper virus to develop productive infection. Until now, there are twelve species described, which AAV2, AAV3, AAV5 e AAV9 were described infecting human beings. In the genital tract, ...
Abortamento humano : detecção molecular de AAV e de HPV em decídua e vilosidade coriônica
(Universidade Federal do Espírito SantoBRMestrado em Doenças InfecciosasPrograma de Pós-Graduação em Doenças InfecciosasUFES, 2007-11-14)
Pregnancy failure is a common event often of unknown cause. Some viruses are suggested as cause of abortion and, among them, adeno-associated virus (AAV), that has never been implicated as a cause of disease. AAV (AAV1-11 ...
Successful transduction with AAV vectors after selective depletion of anti-AAV antibodies by immunoadsorption
(Cell Press, 2020-03-13)
Gene therapy with adeno-associated virus (AAV)-based vectors shows great promise for the gene therapeutic treatment of a broad array of diseases. In fact, the treatment of genetic diseases with AAV vectors is currently the ...
Adenoassociated Virus Type 2-Induced Inhibition of the Human Papillomavirus Type 18 Promoter in Transgenic Mice
(Academic PressMicrobiología MolecularNueva York, Estados Unidos, 2022)
AAV8-vectored suprachoroidal gene transfer produces widespread ocular transgene expression
(American Society for Clinical Investigation, 2019-11)
There has been great progress in ocular gene therapy, but delivery of viral vectors to the retinal pigmented epithelium (RPE) and retina can be challenging. Subretinal injection, the preferred route of delivery for most ...
ANCA-Associated Vasculitis in Latin America A Systematic Literature Review: About Their Epidemiology and Their Clinical Features
(Wolters Kluwer Health, 2022)
Most of the existing literature, including epidemiological studies and clinical trials, on antineutrophil cytoplasmic antibodies (ANCA)–associated vasculitis (AAV) include North American (mainly United States and Canada), ...
AAV gene therapy for alcoholism: inhibition of mitochondrial aldehyde dehydrogenase enzyme expression in hepatoma cells
(Mary Ann Liebert, Inc., 2017)
Most ethanol is broken down in the liver in two steps by alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH2) enzymes, which metabolize down ethanol into acetaldehyde and then acetate. Some individuals from the ...